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Total database: 17430
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Target
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Hasil Pencarian (2)

Frovatriptan Approved DB00998
small molecule | CAS: 158747-02-5

Frovatriptan is a triptan drug developed by Vernalis for the treatment of migraine headaches, in particular those associated with menstruation. Frovatriptan causes vasoconstriction of arteries and veins that supply blood to the head.

Kategori:
Agents that produce hypertensionAminesAnalgesics +23
Target Protein:
5-hydroxytryptamine receptor 1D5-hydroxytryptamine receptor 1B
Gen Terkait:
GNB3
Waktu Paruh26 hours
Vol. Distribusi* 4.2 L/kg [males] …
Klirens* 220 mL/min [male …
Genetik 1 Varian
Zolmitriptan Approved DB00315
small molecule | CAS: 139264-17-8

Zolmitriptan is a member of the triptan class of 5-hydroxytryptamine(5-HT)<sub>1B/1D/(1F)</sub> receptor agonists used to treat acute migraine.[A462, L12978] [Sumatriptan] was the first triptan to be developed, but had poor oral bioavailability and lipophilic…

Kategori:
Agents that produce hypertensionAminesAnalgesics +24
Target Protein:
5-hydroxytryptamine receptor 1B5-hydroxytryptamine receptor 1D5-hydroxytryptamine receptor 1F +5
Gen Terkait:
GNB3
Waktu ParuhZolmitriptan has a …
Vol. DistribusiZolmitriptan has a …
KlirensZolmitriptan has a …
Genetik 1 Varian