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Total database: 17430
Struktur (SMILES)
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Target
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Hasil Pencarian (2)

Foscarnet Approved DB00529
small molecule | CAS: 4428-95-9

An antiviral agent used in the treatment of cytomegalovirus retinitis. Foscarnet also shows activity against human herpes viruses and HIV.

Kategori:
AcetatesAcids, AcyclicAnti-Infective Agents +17
Target Protein:
DNA polymerase catalytic subunitDNA polymerase catalytic subunit
Waktu Paruh3.3-6.8 hours
Vol. Distribusi-
Klirens* 2.13 +/- 0.71 mL/…
Genetik -
Maribavir Approved DB06234
small molecule | CAS: 176161-24-3

Maribavir is an inhibitor of the cytomegalovirus (CMV; HHV5) pUL97 kinase which is used to treat CMV infections in patients post-transplantation.[L39322] Most standard CMV therapies, such as [ganciclovir] or [foscarnet], target CMV DNA polymerase - while gene…

Kategori:
Anti-Infective AgentsAntiinfectives for Systemic UseAntiviral Agents +14
Target Protein:
Serine/threonine protein kinase UL97
Waktu ParuhIn post-transplant …
Vol. DistribusiThe mean apparent s…
KlirensIn post-transplant …
Genetik -