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Flunarizine Approved DB04841

small molecule | CAS: 52468-60-7

Flunarizine is a selective calcium entry blocker with calmodulin binding properties and histamine H1 blocking activity. It is effective in the prophylaxis of migraine, occlusive peripheral vascular disease, vertigo of central and peripheral origin, and as an …

Kategori:

Agents causing hyperkalemiaAntiarrhythmic agentsAnticonvulsants +24

Target Protein:

Voltage-dependent P/Q-type calcium channel subunit alpha-1AVoltage-dependent T-type calcium channel subunit alpha-1GVoltage-dependent T-type calcium channel subunit alpha-1H +3

Waktu Paruh18 days

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Verapamil Approved DB00661

small molecule | CAS: 52-53-9

Verapamil is a phenylalkylamine calcium channel blocker used in the treatment of high blood pressure, heart arrhythmias, and angina,[L8791] and was the first calcium channel antagonist to be introduced into therapy in the early 1960s.[A188514] It is a member …

Kategori:

ACE Inhibitors and Calcium Channel BlockersAdrenergic alpha-1 Receptor AntagonistsAdrenergic alpha-Antagonists +50

Target Protein:

Voltage-dependent L-type calcium channel subunit alpha-1CVoltage-dependent N-type calcium channel subunit alpha-1BVoltage-dependent P/Q-type calcium channel subunit alpha-1A +10

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Hasil Pencarian (2)