Hasil Pencarian (2)
small molecule | CAS: 738606-46-7
High levels of LDL cholesterol (LDL-C) are a major risk factor for cardiovascular events. Caused by genetic mutations or lifestyle factors, hypercholesterolemia can significantly reduce quality of life and increase the risk of mortality from cardiovascular di…
Kategori:
Acids, AcyclicAdenosine Triphosphate-Citrate Lyase InhibitorAdenosine Triphosphate-Citrate Lyase Inhibitors
+11
Target Protein:
ATP-citrate synthase
Waktu ParuhThe half-life of be…
Vol. DistribusiThe apparent volume…
KlirensThe clearance (CL/F…
Genetik
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small molecule | CAS: 163222-33-1
Ezetimibe is a lipid-lowering compound that inhibits intestinal cholesterol and phytosterol absorption. The discovery and research of this drug began in the early 1990s, after the intravenous administration of radiolabelled ezetimibe in rats revealed that it …
Kategori:
Anticholesteremic AgentsAzetinesBCRP/ABCG2 Substrates
+20
Target Protein:
NPC1-like intracellular cholesterol transporter 1Sterol O-acyltransferase 1Aminopeptidase N
Waktu ParuhBoth ezetimibe and …
Vol. DistribusiThe relative volume…
KlirensThere are no pharma…
Genetik
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