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Total database: 17430
Struktur (SMILES)
2 (100.0%)
Target
1 (50.0%)
Genomik
0 (0%)
Referensi
2 (100.0%)

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Hasil Pencarian (2)

Esaxerenone DB15207
small molecule | CAS: 1632006-28-0

Esaxerenone is under investigation in clinical trial NCT02722265 (Long-term Study of CS-3150 as Monotherapy or in Combination With Other Antihypertensive Drug in Japanese Patients With Essential Hypertension).

Kategori:
Sulfur Compounds
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Finerenone Approved DB16165
small molecule | CAS: 1050477-31-0

Finerenone, or BAY 94-8862, is a mineralocorticoid receptor antagonist indicated to reduce the risk of sustained decline in glomerular filtration rate, end stage kidney disease, cardiovascular death, heart attacks, and hospitalization due to heart failure in …

Kategori:
Agents causing hyperkalemiaCytochrome P-450 CYP2C8 SubstratesCytochrome P-450 CYP3A Substrates +6
Target Protein:
Mineralocorticoid receptor
Waktu ParuhThe half life of a …
Vol. DistribusiThe volume of distr…
KlirensThe systemic cleara…
Genetik -