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Total database: 17430
Struktur (SMILES)
2 (100.0%)
Target
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Genomik
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Referensi
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Hasil Pencarian (2)

Dihydroergotamine Approved DB00320
small molecule | CAS: 511-12-6

A 9,10alpha-dihydro derivative of [ergotamine]. Dihydroergotamine is used as an abortive therapy for migraines.[L38469] Its use has largely been supplanted by triptans in current therapy due to the class's greater selectivity and more favourable side effect p…

Kategori:
Adrenergic alpha-1 Receptor AntagonistsAdrenergic alpha-AntagonistsAdrenergic Antagonists +37
Target Protein:
5-hydroxytryptamine receptor 1B5-hydroxytryptamine receptor 1D5-hydroxytryptamine receptor 1F +13
Waktu ParuhDHE exhibits a biph…
Vol. DistribusiDHE has a steady-st…
KlirensThe total clearance…
Genetik -
Ergotamine Approved DB00696
small molecule | CAS: 113-15-5

A vasoconstrictor found in ergot of Central Europe. It is an alpha-1 selective adrenergic agonist and is commonly used in the treatment of migraine disorders.

Kategori:
Adrenergic AgentsAdrenergic alpha-1 Receptor AntagonistsAdrenergic alpha-Antagonists +39
Target Protein:
5-hydroxytryptamine receptor 1D5-hydroxytryptamine receptor 1B5-hydroxytryptamine receptor 2A +11
Waktu Paruh2 hours
Vol. Distribusi-
Klirens-
Genetik -