Hasil Pencarian (2)
small molecule | CAS: 107724-20-9
Eplerenone, an aldosterone receptor antagonist similar to spironolactone, has been shown to produce sustained increases in plasma renin and serum aldosterone, consistent with inhibition of the negative regulatory feedback of aldosterone on renin secretion. Th…
Kategori:
Agents causing hyperkalemiaAntihypertensive AgentsAntihypertensive Agents Indicated for Hypertension
+19
Target Protein:
Mineralocorticoid receptor
Waktu Paruh4-6 hours
Vol. Distribusi* 43 to 90 L
Klirens* Apparent plasma c…
Genetik
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small molecule | CAS: 1050477-31-0
Finerenone, or BAY 94-8862, is a mineralocorticoid receptor antagonist indicated to reduce the risk of sustained decline in glomerular filtration rate, end stage kidney disease, cardiovascular death, heart attacks, and hospitalization due to heart failure in …
Kategori:
Agents causing hyperkalemiaCytochrome P-450 CYP2C8 SubstratesCytochrome P-450 CYP3A Substrates
+6
Target Protein:
Mineralocorticoid receptor
Waktu ParuhThe half life of a …
Vol. DistribusiThe volume of distr…
KlirensThe systemic cleara…
Genetik
-