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2

Total database: 17430
Struktur (SMILES)
2 (100.0%)
Target
2 (100.0%)
Genomik
0 (0%)
Referensi
2 (100.0%)

Tipe Molekul

Distribusi Wujud Zat

Status Regulasi

Hasil Pencarian (2)

Encainide Approved DB01228
small molecule | CAS: 66778-36-7

All drug products containing encainide hydrochloride. Encainide hydrochloride, formerly marketed as Enkaid capsules, was associated with increased death rates in patients who had asymptomatic heart rhythm abnormalities after a recent heart attack. The manufac…

Kategori:
AmidesAminesAnilides +13
Target Protein:
Sodium channel protein type 5 subunit alpha
Waktu Paruh1-2 hours
Vol. Distribusi-
Klirens-
Genetik -
Flecainide Approved DB01195
small molecule | CAS: 54143-55-4

Flecainide is a Class I anti-arrhythmic agent like [encainide] and [propafenone].[A186880] Flecainide’s development began in 1966 and was first synthesized in 1972 as an attempt to generate new anesthetics.[A186931] It is used to prevent supraventricular and …

Kategori:
Antiarrhythmic agentsAntiarrhythmics, Class IAntiarrhythmics, Class Ic +27
Target Protein:
Sodium channel protein type 4 subunit alphaSodium channel protein type 5 subunit alphaVoltage-gated inwardly rectifying potassium channel KCNH2 +1
Waktu ParuhIn healthy subjects…
Vol. DistribusiThe average volume …
KlirensThe average clearan…
Genetik -