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Total database: 17430
Struktur (SMILES)
2 (100.0%)
Target
2 (100.0%)
Genomik
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Referensi
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Hasil Pencarian (2)

Elagolix Approved DB11979
small molecule | CAS: 834153-87-6

Elagolix has been used in trials studying the basic science and treatment of Endometriosis, Folliculogenesis, Uterine Fibroids, Heavy Uterine Bleeding, and Heavy Menstrual Bleeding. As of 24 July 2018, however, the U.S. Food and Drug Administration (FDA) appr…

Kategori:
Anti-Gonadotropin-Releasing HormonesAntigonadotropins and Similar AgentsCytochrome P-450 CYP2C19 Inhibitors +16
Target Protein:
Gonadotropin-releasing hormone receptor
Waktu ParuhThe terminal phase …
Vol. DistribusiThe apparent volume…
KlirensThe oral clearance …
Genetik -
Linzagolix Approved DB17083
small molecule | CAS: 935283-04-8

Linzagolix is a non-peptide, selective antagonist of the gonadotropin-releasing hormone (GnRH) receptor. It has been studied for the treatment of estrogen-dependent conditions such as uterine fibroids and endometriosis.[A253642,A253647] It is similar to other…

Kategori:
Anti-Gonadotropin-Releasing HormonesBCRP/ABCG2 SubstratesCytochrome P-450 CYP2C8 Inhibitors +18
Target Protein:
Gonadotropin-releasing hormone receptor
Waktu ParuhThe half-life of li…
Vol. DistribusiAfter seven days of…
KlirensThe geometric mean …
Genetik -