Hasil Pencarian (2)
small molecule | CAS: 116539-59-4
Duloxetine is a dual serotonin and norepinephrine reuptake inhibitor.[label] It was originally discovered in 1993 and developed by Eli Lilly and Company as LY248686.[A178741] Duloxetine first received approval from the FDA in August, 2004 as Cymbalta for the …
Kategori:
Agents producing tachycardiaAnalgesicsAntidepressive Agents
+39
Target Protein:
Sodium-dependent serotonin transporterSodium-dependent noradrenaline transporterSodium-dependent dopamine transporter
Waktu ParuhMean of 12 h with a…
Vol. DistribusiApparent Vd of 1620…
KlirensThere is a large de…
Genetik
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small molecule | CAS: 27203-92-5
Tramadol is a centrally acting synthetic opioid analgesic and SNRI (serotonin/norepinephrine reuptake-inhibitor) that is structurally related to [codeine] and [morphine]. Due to its good tolerability profile and multimodal mechanism of action, tramadol is gen…
Kategori:
Agents producing tachycardiaAgents that reduce seizure thresholdAlcohols
+33
Target Protein:
Mu-type opioid receptorSodium-dependent noradrenaline transporterSodium-dependent serotonin transporter
+12
Waktu ParuhTramadol reported a…
Vol. DistribusiThe volume of distr…
KlirensIn clinical trials,…
Genetik
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