Hasil Filter

10

Total database: 17430
Struktur (SMILES)
4 (40.0%)
Target
6 (60.0%)
Genomik
0 (0%)
Referensi
10 (100.0%)

Tipe Molekul

Distribusi Wujud Zat

Status Regulasi

Hasil Pencarian (10)

AP-001 DB18511
small molecule | CAS: 660430-03-5

Deskripsi belum tersedia.

Kategori:
Dietary FatsDietary Fats, UnsaturatedFats +6
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Cod liver oil DB11321
small molecule | CAS: 8001-69-2

Cod liver oil is extracted from the liver of cod fish and mainly consists of omega-3 fatty acids, eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). Also being a rich source of vitamin A and D, cod liver oil can be taken orally as daily supplements. …

Kategori:
Diet, Food, and NutritionDietary FatsDietary Fats, Unsaturated +8
Waktu ParuhAs cod liver oil co…
Vol. DistribusiAs cod liver oil co…
KlirensAs cod liver oil co…
Genetik -
Doconexent Approved DB03756
small molecule | CAS: 6217-54-5

A mixture of fish oil and primrose oil, doconexent is used as a high-docosahexaenoic acid (DHA) supplement. DHA is a 22 carbon chain with 6 cis double bonds with anti-inflammatory effects. It can be biosythesized from alpha-linolenic acid or commercially manu…

Kategori:
Cytochrome P-450 CYP2C9 InhibitorsCytochrome P-450 CYP2C9 Inhibitors (strength unknown)Cytochrome P-450 CYP2C9 Substrates +11
Target Protein:
Peroxisome proliferator-activated receptor alphaProstaglandin G/H synthase 1Prostaglandin G/H synthase 2 +6
Waktu ParuhApproximately 20 ho…
Vol. DistribusiDHA is the most abu…
Klirens-
Genetik -
Fish oil Approved DB13961
biotech

Fish oil is a component of SMOFLIPID, which was FDA approved in July 2016. It is indicated in adults as a source of calories and essential fatty acids for parenteral nutrition when oral or enteral nutrition is not possible, insufficient, or contraindicated. …

Kategori:
Agents causing hyperkalemiaAntiarrhythmic agentsBradycardia-Causing Agents +8
Target Protein:
Diacylglycerol O-acyltransferase 2Prostaglandin G/H synthase 2Free fatty acid receptor 4 +8
Waktu ParuhThe half-life of EP…
Vol. DistribusiThe volume of distr…
KlirensThe clearance of EP…
Genetik -
Omega-3 fatty acids Approved DB11133
small molecule | CAS: 329042-31-1

Omega-3 fatty acids are polyunsaturated fatty acids (PUFAs) with a double bond at the third carbon atom from the end of the carbon chain. The three types of omega-3 fatty acids involved in human physiology are ?-linolenic acid (ALA) (found in plant oils), eic…

Kategori:
Alimentary Tract and MetabolismBile and Liver TherapyDietary Fats +12
Target Protein:
Peroxisome proliferator-activated receptor gammaPeroxisome proliferator-activated receptor alphaSterol regulatory element-binding protein 1
Waktu ParuhApproximate half-li…
Vol. DistribusiVd of EPA is aproxi…
KlirensClearance of EPA is…
Genetik -
Omega-3-acid ethyl esters Approved DB09539
small molecule | CAS: 308081-97-2

Omega-3-acid ethyl esters are prescription drugs that contain eicosapentaenoic acid-ethyl ester (EPA) and docosahexaenoic acid-ethyl ester (DHA) that are used in combination with changes in diet to lower triglyceride levels in adults with severe (? 500 mg/dL)…

Kategori:
AutacoidsBiological FactorsDiet, Food, and Nutrition +15
Target Protein:
Sterol regulatory element-binding protein 1
Waktu Paruh79 hours ± 47 hours…
Vol. Distribusi82 ± 56L[A18890]
Klirens757 mL/h ± 283mL/h[…
Genetik -
Omega-3-carboxylic acids Approved DB09568
small molecule

The omega-3 carboxylic acid (OM3-CA) is a new formulation of omega-3 fatty acids that present an enhanced bioavailability in the treatment of dyslipidemia. The increased bioavailability is explained because OM3-CA is found in a form of polyunsaturated free f…

Kategori:
Fatty Acids, Omega-3
Target Protein:
Diacylglycerol O-acyltransferase 23-hydroxyacyl-CoA dehydrogenase type-2Enoyl-CoA hydratase, mitochondrial +3
Waktu ParuhThe half-life of OM…
Vol. DistribusiThis pharmacokineti…
KlirensThe registered clea…
Genetik -
small molecule | CAS: 199796-52-6

A combination of [docosahexaenoic Acid] (a natural fatty acid) and [paclitaxel] (an anticancer drug) being studied in the treatment of cancer. It is a type of mitotic inhibitor.

Kategori:
CyclodecanesCycloparaffinsDiterpenes +2
Target Protein:
Apoptosis regulator Bcl-2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
PPI-1040 DB17620
small molecule | CAS: 1436673-69-6

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Vayarin Approved DB09328
biotech

Vayarin is a prescription medical food for the clinical dietary management of certain lipid imbalances blamed to be associated with attention deficit hyperactivity disorder (ADHD) in children. Vayarin contains _Lipirinen_, a proprietary composition containing…

Kategori:
Cytochrome P-450 CYP2E1 InhibitorsCytochrome P-450 CYP2E1 Inhibitors (strength unknown)Cytochrome P-450 Enzyme Inhibitors
Waktu ParuhAbout 2h [L1507]
Vol. Distribusi-
KlirensMainly in the feces…
Genetik -