Hasil Pencarian (2)
small molecule | CAS: 42399-41-7
Diltiazem is a benzothiazepine derivative with antihypertensive and vasodilating properties. Approved in 1982 by the FDA, it is a member of the non-dihydropyridine calcium channel blockers drug class. It works through various mechanisms of action, but it prim…
Kategori:
Agents causing hyperkalemiaAgents for Treatment of Hemorrhoids and Anal Fissures for Topical UseAntiarrhythmic agents
+44
Target Protein:
Voltage-dependent L-type calcium channel subunit alpha-1CVoltage-dependent calcium channel subunit alpha-2/delta-1Voltage-dependent calcium channel gamma-1 subunit
Gen Terkait:
ADRB1
Waktu ParuhThe plasma eliminat…
Vol. DistribusiThe apparent volume…
KlirensFollowing a single …
Genetik
1 Varian
small molecule | CAS: 52-53-9
Verapamil is a phenylalkylamine calcium channel blocker used in the treatment of high blood pressure, heart arrhythmias, and angina,[L8791] and was the first calcium channel antagonist to be introduced into therapy in the early 1960s.[A188514] It is a member …
Kategori:
ACE Inhibitors and Calcium Channel BlockersAdrenergic alpha-1 Receptor AntagonistsAdrenergic alpha-Antagonists
+50
Target Protein:
Voltage-dependent L-type calcium channel subunit alpha-1CVoltage-dependent N-type calcium channel subunit alpha-1BVoltage-dependent P/Q-type calcium channel subunit alpha-1A
+10
Gen Terkait:
ADRB1
Waktu ParuhSingle-dose studies…
Vol. DistribusiVerapamil has a ste…
KlirensSystemic clearance …
Genetik
1 Varian