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Total database: 17430
Struktur (SMILES)
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Target
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Genomik
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Referensi
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Hasil Pencarian (5)

Benzphetamine Approved DB00865
small molecule | CAS: 156-08-1

A sympathomimetic agent with properties similar to dextroamphetamine. It is used in the treatment of obesity. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1222)

Kategori:
Adrenergic AgentsAdrenergic AgonistsAdrenergic alpha-1 Receptor Agonists +28
Target Protein:
Synaptic vesicular amine transporterAlpha-2A adrenergic receptorAlpha-1A adrenergic receptor +1
Waktu Paruh16 to 31 hours
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 461-78-9

A sympathomimetic agent that was formerly used as an anorectic. It has properties similar to those of dextroamphetamine. It has been implicated in lipid storage disorders and pulmonary hypertension. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1223)

Kategori:
Agents producing tachycardiaAgents that produce hypertensionAmines +7
Target Protein:
Sodium-dependent serotonin transporter
Waktu Paruh40 hours
Vol. Distribusi-
Klirens-
Genetik -
Dextroamphetamine Approved DB01576
small molecule | CAS: 51-64-9

Dextroamphetamine is the dextrorotatory enantiomer of amphetamine[A2505]. Dextroamphetamine was approved by the FDA in 2001 for the treatment of attention deficit hyperactivity disorder[L6010,Label].

Kategori:
Agents producing tachycardiaAgents that produce hypertensionAmines +19
Target Protein:
Synaptic vesicular amine transporterSodium-dependent noradrenaline transporterSodium-dependent dopamine transporter +3
Waktu Paruh11.75 hours.[Label]…
Vol. Distribusi195L.[A177247]
Klirens17L/h.[A177247]
Genetik -
Lisdexamfetamine Approved DB01255
small molecule | CAS: 608137-32-2

Lisdexamfetamine is a prodrug of [dextroamphetamine], a central nervous system stimulant known as d-amphetamine,[A40246] covalently attached to the naturally occurring amino acid L-lysine.[A2230] Lisdexamfetamine is the first chemically formulated prodrug sti…

Kategori:
Agents producing tachycardiaAgents that produce hypertensionAmines +17
Target Protein:
Trace amine-associated receptor 1
Waktu ParuhPlasma concentratio…
Vol. DistribusiDextroamphetamine, …
Klirens-
Genetik -
Phenmetrazine Approved DB00830
small molecule | CAS: 134-49-6

A sympathomimetic drug used primarily as an appetite depressant. Its actions and mechanisms are similar to dextroamphetamine.

Kategori:
Agents producing tachycardiaAgents that produce hypertensionAnti-Obesity Agents +8
Target Protein:
Sodium-dependent noradrenaline transporterSodium-dependent dopamine transporter
Waktu Paruh16 to 31 hours
Vol. Distribusi-
Klirens-
Genetik -