Hasil Pencarian (2)
small molecule | CAS: 1492952-76-7
Asciminib is a tyrosine kinase inhibitor (TKI) used in the treatment of chronic-phase Philadelphia chromosome-positive chronic myeloid leukemia (Ph+ CML). More specifically, it is an inhibitor of the ABL1 kinase activity of the BCR-ABL1 fusion protein[L38995]…
Kategori:
Antineoplastic AgentsAntineoplastic and Immunomodulating AgentsBcr-Abl Tyrosine Kinase Inhibitors
+26
Target Protein:
Tyrosine-protein kinase ABL1
Waktu ParuhThe terminal elimin…
Vol. DistribusiAt steady-state, th…
KlirensThe total apparent …
Genetik
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small molecule | CAS: 302962-49-8
Dasatinib is an orally available multikinase inhibitor indicated for the treatment of Philadelphia chromosome (Ph)-positive leukemias.[A2224,L45171] Ph is a chromosomal abnormality found in patients with chronic myelogenous leukemia (CML) and acute lymphocyti…
Kategori:
Antineoplastic AgentsAntineoplastic and Immunomodulating AgentsBcr-Abl Tyrosine Kinase Inhibitors
+31
Target Protein:
Tyrosine-protein kinase ABL1Proto-oncogene tyrosine-protein kinase SrcEphrin type-A receptor 2
+20
Waktu ParuhThe terminal half-l…
Vol. DistribusiDasatinib has an ap…
KlirensThe clearance of da…
Genetik
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