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3

Total database: 17430
Struktur (SMILES)
3 (100.0%)
Target
2 (66.7%)
Genomik
0 (0%)
Referensi
3 (100.0%)

Tipe Molekul

Distribusi Wujud Zat

Status Regulasi

Hasil Pencarian (3)

Acediasulfone DB08926
small molecule | CAS: 80-03-5

Acediasulfone (INN) is an antimicrobial and antimalarial long-acting prodrug of dapsone.

Kategori:
Sulfur Compounds
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Clofazimine Approved DB00845
small molecule | CAS: 2030-63-9

Clofazimine is a highly lipophilic antimicrobial riminophenazine dye used in combination with other agents, such as [dapsone], for the treatment of leprosy. It was originally described in 1957 and was the prototypical riminophenazine dye - a bright-red dye th…

Kategori:
Anti-Bacterial AgentsAnti-Infective AgentsAnti-Inflammatory Agents +23
Target Protein:
Peroxisome proliferator-activated receptor gammaPotassium voltage-gated channel subfamily A member 3
Waktu ParuhThe mean eliminatio…
Vol. DistribusiClofazimine is high…
Klirens-
Genetik -
Dapsone Approved DB00250
small molecule | CAS: 80-08-0

A sulfone active against a wide range of bacteria but mainly employed for its actions against mycobacterium leprae. Its mechanism of action is probably similar to that of the sulfonamides which involves inhibition of folic acid synthesis in susceptible organi…

Kategori:
Anti-Acne PreparationsAnti-Acne Preparations for Topical UseAnti-Bacterial Agents +32
Target Protein:
Inactive dihydropteroate synthase 2Dihydropteroate synthase
Waktu Paruh28 hours (range 10-…
Vol. Distribusi-
Klirens-
Genetik -