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Total database: 17430
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Hasil Pencarian (4)

Clobetasol Approved DB11750
small molecule | CAS: 25122-41-2

Clobetasol is under investigation for the treatment of Scleroderma. Clobetasol has been investigated for the prevention of Psoriasis and Cutaneous Atrophy Due to Corticosteroids.

Kategori:
Adrenal Cortex HormonesAnti-Inflammatory AgentsCorticosteroid Hormone Receptor Agonists +22
Target Protein:
Phospholipase A2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Clobetasol propionate Approved DB01013
small molecule | CAS: 25122-46-7

Clobetasol propionate is a prednisolone derivative with higher specificity for glucocorticoid receptors than mineralocorticoid receptors.[L11815] It has demonstrated superior activity compared to [fluocinonide][A190963] and was first described in the literatu…

Kategori:
Adrenal Cortex HormonesAnti-Inflammatory AgentsCorticosteroids +21
Target Protein:
Glucocorticoid receptorAnnexin A1Mineralocorticoid receptor
Waktu ParuhData regarding the …
Vol. DistribusiData regarding the …
KlirensData regarding the …
Genetik -
Halcinonide Approved DB06786
small molecule | CAS: 3093-35-4

Halcinonide is a corticosteroid indicated for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses, and is distributed as a cream and ointment. Halcinonide is marketed under the brand name Halog® by Ranbaxy Labora…

Kategori:
Adrenal Cortex HormonesAnti-Inflammatory AgentsCorticosteroid Hormone Receptor Agonists +13
Target Protein:
Steroid hormone receptor ERR1Steroid hormone receptor ERR2Estrogen-related receptor gamma +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Ulobetasol Approved DB00596
small molecule | CAS: 98651-66-2

Ulobetasol is a highly potent corticosteroid.[A215597] It is structurally related to [clobetasol].[A215597] Due to its high potency, it is mainly prescribed in the treatment of severe plaque psoriasis and corticosteroid responsive dermatoses.[L15047,L15052,L1…

Kategori:
Adrenal Cortex HormonesAnti-Inflammatory AgentsAntipsoriatics +15
Target Protein:
Steroid hormone receptor ERR1Steroid hormone receptor ERR2Estrogen-related receptor gamma +1
Waktu Paruh_In vitro_ experime…
Vol. Distribusi-
Klirens-
Genetik -