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Total database: 17430
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Target
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Hasil Pencarian (5)

Citalopram Approved DB00215
small molecule | CAS: 59729-33-8

Citalopram is an antidepressant belonging to the class of selective _serotonin-reuptake inhibitors_ (SSRIs) widely used to treat the symptoms of depression. It is a racemic bicyclic phthalate derivate and is the only compound with a tertiary amine and 2 nitro…

Kategori:
AminesAntidepressive AgentsAntidepressive Agents Indicated for Depression +41
Target Protein:
Sodium-dependent serotonin transporterHistamine H1 receptor
Gen Terkait:
ABCB1 HTR2A GRIK4 +3
Waktu ParuhThe mean terminal h…
Vol. DistribusiThe volume of distr…
KlirensThe systemic cleara…
Genetik 6 Varian
Escitalopram Approved DB01175
small molecule | CAS: 128196-01-0

Escitalopram is a selective serotonin re-uptake inhibitor (SSRI) and the S-enantiomer of racemic [citalopram].[A185420] It is used to restore serotonergic function in the treatment of depression and anxiety.[L8513,L8516,L8522] Escitalopram is approximately 15…

Kategori:
AminesAnticholinergic AgentsAntidepressive Agents +35
Target Protein:
Sodium-dependent serotonin transporterMuscarinic acetylcholine receptor M1Histamine H1 receptor +8
Gen Terkait:
CYP2C19 CYP2C19 SLC6A4
Waktu ParuhThe elimination hal…
Vol. DistribusiEscitalopram appear…
KlirensThe oral plasma cle…
Genetik 3 Varian
Sertraline Approved DB01104
small molecule | CAS: 79617-96-2

Sertraline is a popular antidepressant medication commonly known as a selective serotonin reuptake inhibitor (SSRI), and is similar to drugs such as [Citalopram] and [Fluoxetine]. Despite marked structural differences between compounds in this drug class, SSR…

Kategori:
Agents that reduce seizure thresholdAminesAntidepressive Agents +39
Target Protein:
Sodium-dependent serotonin transporterSodium-dependent dopamine transporterSigma receptor +2
Gen Terkait:
CYP2C19 CYP2C19
Waktu ParuhThe elimination hal…
Vol. DistribusiSertraline is widel…
KlirensIn pharmacokinetic …
Genetik 2 Varian
Talopram DB09190
small molecule | CAS: 7182-51-6

Talopram is a selective norepinephrine reuptake inhibitor (SNRI) that is structurally similar to citalopram and melitracen. It was researched in the 1960s and 1970s but never marketed.

Kategori:
Adrenergic Uptake InhibitorsAminesAntidepressive Agents +3
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Talsupram DB09191
small molecule | CAS: 21489-20-3

Talsupram is a selective norepinephrine reuptake inhibitor (NRI). It was under research for the treatment of depression in 1960 and 1970 but it was never marketed. Talsupram presents a similar structure to [citalopram].

Kategori:
Sulfur Compounds
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -