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2

Total database: 17430
Struktur (SMILES)
1 (50.0%)
Target
2 (100.0%)
Genomik
0 (0%)
Referensi
2 (100.0%)

Tipe Molekul

Distribusi Wujud Zat

Status Regulasi

Hasil Pencarian (2)

Cholestyramine Approved DB01432
small molecule | CAS: 11041-12-6

Cholestyramine or colestyramine is a bile acid sequestrant. Bile acid sequestrants are polymeric compounds which serve as ion exchange resins. Cholestyramine resin is quite hydrophilic, but insoluble in water.

Kategori:
Anion Exchange ResinsAnticholesteremic AgentsBile Acid Sequestrants +14
Target Protein:
Bile acids
Waktu Paruh6 minutes
Vol. Distribusi-
Klirens-
Genetik -
Maralixibat Approved DB16226
small molecule | CAS: 716313-53-0

Maralixibat (also known as SHP625, LUM001, and lopixibat) is an ileal bile acid transporter inhibitor, like [odevixibat].[A236823,A239249,L38834] Maralixibat is indicated for the treatment of cholestatic pruritus in patients with Alagille syndrome.[L38834] …

Kategori:
Alimentary Tract and MetabolismBile and Liver TherapyBile Therapy +9
Target Protein:
Ileal sodium/bile acid cotransporterHepatic sodium/bile acid cotransporter
Waktu ParuhThe mean half life …
Vol. Distribusi-
Klirens-
Genetik -