Hasil Filter

5

Total database: 17430
Struktur (SMILES)
5 (100.0%)
Target
4 (80.0%)
Genomik
2 (40.0%)
Referensi
5 (100.0%)

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Hasil Pencarian (5)

Beclamide DB09011
small molecule | CAS: 501-68-8

Beclamide (N-benzyl-B-chloropropionamide) is a no longer used drug that possesses anticonvulsant and sedative activity. It was studied in the 1950s for generalised tonic-clonic seizures but was not effective for absence seizures.

Kategori:
Acids, AcyclicAnticonvulsantsCentral Nervous System Depressants +4
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Chlorpropamide Approved DB00672
small molecule | CAS: 94-20-2

Chlorpropamide is an oral antihyperglycemic agent used for the treatment of non-insulin-dependent diabetes mellitus (NIDDM). It belongs to the sulfonylurea class of insulin secretagogues, which act by stimulating ? cells of the pancreas to release insulin. Su…

Kategori:
Alimentary Tract and MetabolismAmidesBenzene Derivatives +17
Target Protein:
ATP-binding cassette sub-family C member 8ATP-sensitive inward rectifier potassium channel 10
Waktu ParuhApproximately 36 ho…
Vol. Distribusi-
Klirens-
Genetik -
Glipizide Approved DB01067
small molecule | CAS: 29094-61-9

Glipizide is an oral hypoglycemic agent in the second-generation sulfonylurea drug class that is used to control blood sugar levels in patients with type 2 diabetes mellitus. It was first introduced in 1984 [A179491] and is available in various countries incl…

Kategori:
Alimentary Tract and MetabolismBlood Glucose Lowering AgentsBSEP/ABCB11 Substrates +11
Target Protein:
ATP-binding cassette sub-family C member 8ATP-sensitive inward rectifier potassium channel 10Peroxisome proliferator-activated receptor gamma
Gen Terkait:
CYP2C9
Waktu ParuhThe mean terminal e…
Vol. DistribusiThe mean volume of …
KlirensThe mean total body…
Genetik 1 Varian
Tolazamide Approved DB00839
small molecule | CAS: 1156-19-0

A sulphonylurea hypoglycemic agent with actions and uses similar to those of chlorpropamide.

Kategori:
Alimentary Tract and MetabolismAmidesBenzene Derivatives +15
Target Protein:
Sulfonylurea receptor 1, Kir6.2ATP-sensitive inward rectifier potassium channel 10
Waktu ParuhThe average biologi…
Vol. Distribusi-
Klirens-
Genetik -
Tolbutamide Approved DB01124
small molecule | CAS: 64-77-7

Tolbutamide is an oral antihyperglycemic agent used for the treatment of non-insulin-dependent diabetes mellitus (NIDDM). It is structurally similar to acetohexamide, chlorpropamide and tolazamide and belongs to the sulfonylurea class of insulin secretagogues…

Kategori:
Alimentary Tract and MetabolismAmidesBenzene Derivatives +25
Target Protein:
ATP-binding cassette sub-family C member 9ATP-binding cassette sub-family C member 8ATP-sensitive inward rectifier potassium channel 1
Gen Terkait:
CYP2C9
Waktu ParuhApproximately 7 hou…
Vol. Distribusi-
Klirens-
Genetik 1 Varian