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Total database: 17430
Struktur (SMILES)
4 (100.0%)
Target
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Genomik
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Distribusi Wujud Zat

Status Regulasi

Hasil Pencarian (4)

Chlorpheniramine Approved DB01114
small molecule | CAS: 132-22-9

A histamine H1 antagonist used in allergic reactions, hay fever, rhinitis, urticaria, and asthma. It has also been used in veterinary applications. One of the most widely used of the classical antihistaminics, it generally causes less drowsiness and sedation …

Kategori:
Anti-Allergic AgentsAntidepressive AgentsAntihistamines for Systemic Use +27
Target Protein:
Histamine H1 receptorSodium-dependent serotonin transporterSodium-dependent noradrenaline transporter +1
Waktu Paruh21-27 hours
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 25523-97-1

Dexchlorpheniramine is a potent S-enantiomer of chlorpheniramine. The salt form dexchlorpheniramine maleate as the active ingredient is available as a prescription drug indicated for adjunctive therapy for allergic and anaphylactic reactions. It is an antihis…

Kategori:
Agents that reduce seizure thresholdAntihistamines for Systemic UseCytochrome P-450 CYP2D6 Inhibitors +13
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Dexchlorpheniramine maleate Approved DB09555
small molecule | CAS: 2438-32-6

Dexchlorpheniramine is the S-enantiomer of chlorpheniramine which is a 1st generation anti-histamine. Dexchlorpheniramine has more pharmacological activity than the R and so is more potent than the racemic mixture.

Kategori:
Agents that reduce seizure thresholdCytochrome P-450 CYP2D6 InhibitorsCytochrome P-450 CYP2D6 Inhibitors (strength unknown) +16
Target Protein:
Histamine H1 receptor
Waktu Paruh20-30 h
Vol. Distribusi321L
Klirens9.8L/h
Genetik -
Pheniramine Approved DB01620
small molecule | CAS: 86-21-5

Pheniramine is a first-generation antihistamine in the alkylamine class, similar to [brompheniramine] and [chlorpheniramine].[A181628] It is used in some over-the-counter allergy as well as cold & flu products in combination with other drugs. Pheniramine's …

Kategori:
Anti-Allergic AgentsAntihistamines for Systemic UseAntihistamines for Topical Use +10
Target Protein:
Histamine H4 receptorHistamine H1 receptorNuclear receptor subfamily 1 group I member 3
Waktu ParuhThe terminal half-l…
Vol. Distribusi-
Klirens-
Genetik -