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4

Total database: 17430
Struktur (SMILES)
3 (75.0%)
Target
4 (100.0%)
Genomik
0 (0%)
Referensi
4 (100.0%)

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Distribusi Wujud Zat

Status Regulasi

Hasil Pencarian (4)

Anidulafungin Approved DB00362
biotech | CAS: 166663-25-8

Anidulafungin or Eraxis is an anti-fungal drug manufactured by Pfizer that gained approval by the Food and Drug Administration (FDA) in February 21, 2006; it was previously known as LY303366. There is preliminary evidence that it has a similar safety profile …

Kategori:
Amino Acids, Peptides, and ProteinsAnti-Infective AgentsAntifungal Agents +6
Target Protein:
1,3-beta-glucan synthase component FKS11,3-beta-glucan synthase component GSC2
Waktu Paruh40-50 hours
Vol. Distribusi* 30 to 50 L
Klirens* 1 L/h
Genetik -
Caspofungin Approved DB00520
small molecule | CAS: 162808-62-0

Caspofungin (brand name Cancidas worldwide) is an antifungal drug and the first member of a new drug class called the echinocandins, as coined by Merck & Co., Inc. It is typically administered intravenously. It shows activity against infections with Aspergill…

Kategori:
Amino Acids, Peptides, and ProteinsAnti-Infective AgentsAntifungal Agents +18
Target Protein:
1,3-beta-glucan synthase component FKS11,3-beta-glucan synthase component GSC2
Waktu Paruh9-11 hours
Vol. Distribusi-
Klirens* 12 mL/min [After …
Genetik -
Ibrexafungerp Approved DB12471
small molecule | CAS: 1207753-03-4

Ibrexafungerp, also known as SCY-078 or MK-3118, is a novel enfumafungin derivative oral triterpene antifungal approved for the treatment of vulvovaginal candidiasis (VVC), also known as a vaginal yeast infection.[A235384,L34349] It was developed out of a nee…

Kategori:
Anti-Infective AgentsAntifungal AgentsAntiinfectives for Systemic Use +17
Target Protein:
1,3-beta-glucan synthase component GSC2GTP-binding protein RHO1
Waktu ParuhThe elimination hal…
Vol. DistribusiThe volume of distr…
KlirensClearance values of…
Genetik -
Rezafungin Approved DB16310
small molecule | CAS: 1396640-59-7

Rezafungin is an echinocandin antifungal drug.[A258393,L45633] Unlike other echinocandins such as [caspofungin] and [micafungin], rezafungin has long?acting pharmacokinetics and a high stability that allows for it to have long dosing intervals maintaining hig…

Kategori:
Amino Acids, Peptides, and ProteinsAnti-Infective AgentsAntifungal Agents +8
Target Protein:
1,3-beta-glucan synthase component FKS11,3-beta-glucan synthase component GSC2
Waktu ParuhRezafungin has a te…
Vol. DistribusiRezafungin has a vo…
KlirensRezafungin has an e…
Genetik -