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Total database: 17430
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Hasil Pencarian (4)

Candesartan DB13919
small molecule | CAS: 139481-59-7

Candesartan is an angiotensin-receptor blocker (ARB) that may be used alone or with other agents to treat hypertension. It is available as a prodrug in the form of [candesartan cilexetil].

Kategori:
Agents Acting on the Renin-Angiotensin SystemAgents causing hyperkalemiaAngiotensin 2 Receptor Blocker +22
Target Protein:
Type-1 angiotensin II receptor
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Candesartan cilexetil Approved DB00796
small molecule | CAS: 145040-37-5

Candesartan is an angiotensin-receptor blocker (ARB) that may be used alone or with other agents to treat hypertension. It is administered orally as the prodrug, candesartan cilexetil, which is rapidly converted to its active metabolite, candesartan, during a…

Kategori:
Agents Acting on the Renin-Angiotensin SystemAgents causing hyperkalemiaAngiotensin 2 Receptor Blocker +16
Target Protein:
Type-1 angiotensin II receptor
Waktu ParuhApproximately 9 hou…
Vol. Distribusi* 0.13 L/kg
Klirens* 0.37 mL/min/kg
Genetik -
Olmesartan Approved DB00275
small molecule | CAS: 144689-24-7

Olmesartan belongs to the angiotensin II receptor blocker (ARB) family of drugs, which also includes [telmisartan], [candesartan], [losartan], [valsartan], and [irbesartan]. ARBs selectively bind to angiotensin receptor 1 (AT1) and prevent the protein angiote…

Kategori:
Agents Acting on the Renin-Angiotensin SystemAgents causing hyperkalemiaAngiotensin 2 Receptor Blocker +15
Target Protein:
Type-1 angiotensin II receptor
Waktu ParuhThe mean plasma olm…
Vol. Distribusi17 L[L5566]
KlirensTotal plasma cleara…
Genetik -
Valsartan Approved DB00177
small molecule | CAS: 137862-53-4

Valsartan belongs to the angiotensin II receptor blocker (ARB) family of drugs, which also includes [telmisartan], [candesartan], [losartan], [olmesartan], and [irbesartan]. ARBs selectively bind to angiotensin receptor 1 (AT1) and prevent the protein angiote…

Kategori:
Agents Acting on the Renin-Angiotensin SystemAgents causing angioedemaAgents causing hyperkalemia +22
Target Protein:
Type-1 angiotensin II receptor
Waktu ParuhAfter intravenous (…
Vol. DistribusiThe steady-state vo…
KlirensFollowing intraveno…
Genetik -