Hasil Pencarian (2)
small molecule | CAS: 1051375-10-0
Cabotegravir, or GSK1265744, is an HIV-1 integrase inhibitor that is prescribed with the non-nucleoside reverse transcriptase inhibitor, [rilpivirine].[A227668,L31188,L31193] Early research into cabotegravir showed it had lower oral bioavailability than [dolu…
Kategori:
Anti-HIV AgentsAnti-Infective AgentsAnti-Retroviral Agents
+17
Target Protein:
IntegraseGag-Pol polyprotein
Waktu ParuhThe mean half life …
Vol. DistribusiData regarding the …
KlirensData regarding the …
Genetik
-
small molecule | CAS: 500287-72-9
Rilpivirine is non-nucleoside reverse transcriptase inhibitor (NNRTI) which is used for the treatment of HIV-1 infections in treatment-naive patients.[A31328] It is a diarylpyrimidine derivative.[A31329] The internal conformational flexibility of rilpivirine …
Kategori:
Anti-HIV AgentsAnti-Infective AgentsAnti-Retroviral Agents
+43
Target Protein:
Reverse transcriptase/RNaseHSodium channel protein type 10 subunit alphaGag-Pol polyprotein
+1
Waktu ParuhRilpivirine has a t…
Vol. DistribusiIn HIV-1 patients, …
KlirensIn HIV-1 patients, …
Genetik
-