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4

Total database: 17430
Struktur (SMILES)
4 (100.0%)
Target
2 (50.0%)
Genomik
0 (0%)
Referensi
4 (100.0%)

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Distribusi Wujud Zat

Status Regulasi

Hasil Pencarian (4)

Anagrelide Approved DB00261
small molecule | CAS: 68475-42-3

Anagrelide is a platelet-reducing agent used to lower dangerously elevated platelet levels (i.e. to treat thrombocythemia) in patients with myeloproliferative neoplasms.[L14153] It is an oral imidazoquinazoline that was first approved for use in the US in 199…

Kategori:
Agents producing tachycardiaAntineoplastic AgentsAntineoplastic and Immunomodulating Agents +18
Target Protein:
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A
Waktu ParuhThe t<sub>1/2</sub>…
Vol. Distribusi-
Klirens-
Genetik -
Busulfan Approved DB01008
small molecule | CAS: 55-98-1

Busulfan is a bifunctional alkylating agent, having a selective immunosuppressive effect on bone marrow. It is not a structural analog of the nitrogen mustards. It has been used in the palliative treatment of chronic myeloid leukemia (myeloid leukemia, chroni…

Kategori:
AlcoholsAlkanesAlkanesulfonates +25
Target Protein:
DNA
Waktu Paruh2.6 hours
Vol. Distribusi-
Klirens* 2.52 ml/min/kg [F…
Genetik -
Mannitol busulfan Approved DB12097
small molecule | CAS: 1187-00-4

Mm has been used in trials studying the treatment of Cocaine Dependence and Diabetes Mellitus, Type 2.

Kategori:
Agents causing hyperkalemia
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Treosulfan Approved DB11678
small molecule | CAS: 299-75-2

Treosulfan is under investigation in Allogeneic Haematopoietic Stem Cell Transplantation. Treosulfan has been investigated for the treatment of Lymphoblastic Leukemia, Acute, Childhood.

Kategori:
AlcoholsAlkanesAlkanesulfonates +14
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -