Hasil Pencarian (2)
small molecule | CAS: 36505-84-7
Buspirone is a novel anxiolytic agent with a unique structure and a pharmacological profile. Belonging to the azaspirodecanedione drug class,[A180991] buspirone is a serotonin 5-HT<sub>1A</sub> receptor agonist that is not chemically or pharmacologically rela…
Kategori:
Agents that produce hypertensionAntidepressive AgentsAzaspirodecanedione Derivatives
+22
Target Protein:
5-hydroxytryptamine receptor 1AD(2) dopamine receptorD(3) dopamine receptor
+2
Waktu ParuhIn a single-dose ph…
Vol. DistribusiIn a pharmacokineti…
KlirensIn a pharmacokineti…
Genetik
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small molecule | CAS: 83928-76-1
Gepirone, an azapirone, is a pharmacologic analog of [buspirone] that acts selectively on the pre- and post-synaptic 5HT<sub>1A</sub> receptors. Although earlier clinical trials showed promising results for gepirone, its formulation as an immediate-release ta…
Kategori:
Anti-Anxiety AgentsAntidepressive AgentsCentral Nervous System Agents
+12
Target Protein:
5-hydroxytryptamine receptor 1A
Waktu ParuhThe mean terminal h…
Vol. DistribusiThe apparent volume…
KlirensAfter the administr…
Genetik
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