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Total database: 17430
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Target
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Hasil Pencarian (3)

Bupivacaine Approved DB00297
small molecule | CAS: 38396-39-3

Bupivacaine is a widely used local anesthetic agent.

Kategori:
Agents that reduce seizure thresholdAmidesAmines +19
Target Protein:
Sodium channel protein type 10 subunit alphaProstaglandin E2 receptor EP1 subtype
Waktu Paruh2.7 hours in adults…
Vol. Distribusi-
Klirens-
Genetik -
Levobupivacaine Approved DB01002
small molecule | CAS: 27262-47-1

Levobupivacaine is an amino-amide local anaesthetic drug belonging to the family of n-alkylsubstituted pipecoloxylidide. It is the S-enantiomer of bupivacaine. Levobupivacaine hydrochloride is commonly marketed by AstraZeneca under the trade name Chirocaine.…

Kategori:
AmidesAminesAnesthetics +15
Target Protein:
Sodium channel protein type 10 subunit alpha
Waktu Paruh3.3 hours
Vol. Distribusi66.91 ±18.23 L [aft…
Klirens39.06 ±13.29 L/h [a…
Genetik -
Mepivacaine Approved DB00961
small molecule | CAS: 96-88-8

A local anesthetic that is chemically related to bupivacaine but pharmacologically related to lidocaine. It is indicated for infiltration, nerve block, and epidural anesthesia. Mepivacaine is effective topically only in large doses and therefore should not be…

Kategori:
AmidesAnestheticsAnesthetics, Local +10
Target Protein:
Sodium channel protein type 10 subunit alpha
Waktu ParuhThe half-life of me…
Vol. Distribusi-
Klirens-
Genetik -