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Hasil Pencarian (3)

Brexucabtagene autoleucel Approved DB15699
biotech

Mantle cell lymphoma is a heterogeneous sub-category of non-Hodgkin's lymphoma that can be classified as either an aggressive nodal or an indolent leukemic non-nodal variant. Despite the introduction of Bruton's tyrosine kinase (BTK) inhibitors such as [ibrut…

Kategori:
Amino Acids, Peptides, and ProteinsAntineoplastic AgentsAntineoplastic Agents, Immunological +16
Target Protein:
B-lymphocyte antigen CD19
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Idecabtagene vicleucel Approved DB16665
biotech

Multiple myeloma is a cancer where plasma cells rapidly divide out of control.[A232563] These cancerous cells generally express the B-cell maturation antigen, while it is rarely expressed on non-cancerous cells.[A232563] Multiple myeloma is typically treated …

Kategori:
Amino Acids, Peptides, and ProteinsAntineoplastic AgentsAntineoplastic Agents, Immunological +11
Target Protein:
Tumor necrosis factor receptor superfamily member 17
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Lisocabtagene maraleucel Approved DB16582
biotech

Lisocabtagene maraleucel is a chimeric antigen receptor (CAR) T-cell therapy, similar to [brexucabtagene autoleucel] and [axicabtagene ciloleucel].[A228493,L31588] Lisocabtagene maraleucel is a genetically modified autologous T-cell therapy that targets CD19,…

Kategori:
Antineoplastic AgentsAntineoplastic and Immunomodulating AgentsAntineoplastic cell and gene therapy +3
Target Protein:
B-lymphocyte antigen CD19
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -