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Hasil Pencarian (2)

Brentuximab vedotin Approved DB08870
biotech | CAS: 914088-09-8

Brentuximab vedotin, also known as Adcetris®, is an antibody-drug conjugate that combines an anti-CD30 antibody with the drug monomethyl auristatin E (MMAE). It is an anti-neoplastic agent used in the treatment of Hodgkin's lymphoma and systemic anaplastic la…

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntibodies, Monoclonal +35
Target Protein:
Tumor necrosis factor receptor superfamily member 8
Waktu ParuhThe terminal half-l…
Vol. DistribusiMMAE is unlikely to…
KlirensThe liver is the pr…
Genetik -
Enfortumab vedotin Approved DB13007
biotech | CAS: 1346452-25-2

Enfortumab vedotin is an antibody-drug conjugate used in the treatment of patients with advanced, treatment-resistant urothelial cancers.[L10836] It is comprised of a fully human monoclonal antibody targeted against Nectin-4 and a microtubule-disrupting chemo…

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntibodies, Monoclonal +19
Target Protein:
Nectin-4
Waktu ParuhThe elimination hal…
Vol. DistribusiThe estimated stead…
KlirensThe mean clearance …
Genetik -