Hasil Pencarian (2)
biotech | CAS: 2155851-88-8
Axatilimab is a humanized IgG4 monoclonal antibody produced in Chinese hamster ovary cells.[L51194] It is targeted against macrophage colony-stimulating factor 1 receptor (CSF-1R), causing a reduction in circulating levels of monocytes and macrophages respons…
Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntibodies, Monoclonal
+6
Target Protein:
Macrophage colony-stimulating factor 1 receptor
Waktu ParuhThe mean terminal h…
Vol. DistribusiThe volume of distr…
KlirensThe total clearance…
Genetik
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small molecule | CAS: 911417-87-3
Belumosudil is used in the treatment of chronic graft-versus-host disease (GVHD) and has been investigated for the treatment of pulmonary arterial hypertension.[A236634] It is an inhibitor of rho-associated coiled-coil-containing protein kinases (ROCK), with …
Kategori:
AcetatesAcids, AcyclicAmides
+25
Target Protein:
Rho-associated protein kinase 2Rho-associated protein kinase 1
Waktu ParuhThe mean eliminatio…
Vol. DistribusiFollowing a single …
KlirensThe mean clearance …
Genetik
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