Hasil Pencarian (2)
small molecule | CAS: 446-86-6
Azathioprine is a prodrug of 6-mercaptopurine, first synthesized in 1956 by Gertrude Elion, William Lange, and George Hitchings in an attempt to produce a derivative of 6-mercaptopurine with a better therapeutic index.[A189678,A189687,A189690] Azathioprine is…
Kategori:
AntimetabolitesAntineoplastic and Immunomodulating AgentsAntirheumatic Agents
+21
Target Protein:
AmidophosphoribosyltransferaseRas-related C3 botulinum toxin substrate 1
Gen Terkait:
TPMT
TPMT
TPMT
Waktu ParuhThe half life of az…
Vol. DistribusiData regarding the …
KlirensData regarding the …
Genetik
3 Varian
small molecule | CAS: 24280-93-1
Mycophenolic acid is a potent immunosuppressant agent that inhibits _de novo_ purine biosynthesis.[L42165] It was derived from _Penicillium stoloniferum_, and has also shown antibacterial, antifungal and antiviral properties.[A249170]. Mycophenolic acid is us…
Kategori:
Acids, AcyclicAnti-Bacterial AgentsAnti-Infective Agents
+27
Target Protein:
Inosine-5'-monophosphate dehydrogenase 2Inosine-5'-monophosphate dehydrogenase 1
Waktu ParuhThe mean eliminatio…
Vol. DistribusiAt steady state, th…
KlirensThe mean clearance …
Genetik
-