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Total database: 17430
Struktur (SMILES)
6 (100.0%)
Target
5 (83.3%)
Genomik
1 (16.7%)
Referensi
6 (100.0%)

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Distribusi Wujud Zat

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Hasil Pencarian (6)

(R)-Atenolol DB06987
small molecule | CAS: 56715-13-0

Deskripsi belum tersedia.

Target Protein:
LactotransferrinGroup IIE secretory phospholipase A2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Atenolol Approved DB00335
small molecule | CAS: 29122-68-7

Atenolol is a cardioselective beta-blocker used in a variety of cardiovascular conditions. Sir James Black, a Scottish pharmacologist, pioneered the use of beta-blockers for the management of angina pectoris in 1958 for which he received the Nobel Prize.[…

Kategori:
Adrenergic AgentsAdrenergic AntagonistsAdrenergic beta-1 Receptor Antagonists +23
Target Protein:
Beta-1 adrenergic receptorBeta-2 adrenergic receptor
Gen Terkait:
ADRB1
Waktu Paruh6-7 hrs.[label]
Vol. DistribusiTotal Vd of 63.8-11…
KlirensTotal clearance is …
Genetik 1 Varian
Barnidipine DB09227
small molecule | CAS: 104713-75-9

Barnidipine is a long-acting novel calcium antagonist that belongs to the dihydropyridine (DHP) group of calcium channel blockers. Used in the treatment of hypertension, barnidipine displays high affinity for the calcium channels of the smooth muscle cells in…

Kategori:
Agents causing hyperkalemiaAntiarrhythmic agentsBradycardia-Causing Agents +17
Target Protein:
Voltage-dependent L-type calcium channel subunit alpha-1CVoltage-dependent T-type calcium channel subunit alpha-1GVoltage-dependent T-type calcium channel subunit alpha-1H
Waktu ParuhIn a two-compartmen…
Vol. DistribusiAfter administratio…
Klirens-
Genetik -
Esatenolol DB13443
small molecule | CAS: 93379-54-5

Esatenolol is a beta blocker.

Kategori:
Adrenergic AntagonistsAdrenergic beta-AntagonistsAgents causing hyperkalemia +5
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Lacidipine Approved DB09236
small molecule | CAS: 103890-78-4

Lacidipine is a lipophilic dihydropyridine calcium antagonist with an intrinsically slow onset of activity. Due to its long duration of action, lacidipine does not lead to reflex tachycardia [A31536]. It displays specificity in the vascular smooth muscle, whe…

Kategori:
Agents causing hyperkalemiaAntiarrhythmic agentsAntihypertensive Agents +16
Target Protein:
Voltage-dependent L-type calcium channel
Waktu ParuhThe average termina…
Vol. Distribusi-
Klirens-
Genetik -
Nebivolol Approved DB04861
small molecule | CAS: 118457-14-0

Nebivolol is a racemic mixture of 2 enantiomers where one is a beta adrenergic antagonist and the other acts as a cardiac stimulant without beta adrenergic activity.[A182579] Treatment with nebivolol leads to a greater decrease in systolic and diastolic blood…

Kategori:
Adrenergic AgentsAdrenergic AgonistsAdrenergic Antagonists +29
Target Protein:
Beta-1 adrenergic receptorBeta-2 adrenergic receptorBeta-3 adrenergic receptor
Waktu Paruhd-nebivolol has a h…
Vol. DistribusiFor a 20mg dose, d-…
KlirensFor a 20mg dose, th…
Genetik -