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Total database: 17430
Struktur (SMILES)
3 (100.0%)
Target
3 (100.0%)
Genomik
1 (33.3%)
Referensi
3 (100.0%)

Tipe Molekul

Distribusi Wujud Zat

Status Regulasi

Hasil Pencarian (3)

Anastrozole Approved DB01217
small molecule | CAS: 120511-73-1

Anastrozole is a non-steroidal aromatase inhibitor (AI), similar to [letrozole], used to decrease circulating estrogen levels in the treatment of postmenopausal women with estrogen-responsive breast cancer.[L8863] Anastrozole is also related to [exemestane], …

Kategori:
Antineoplastic AgentsAntineoplastic Agents, HormonalAntineoplastic and Immunomodulating Agents +30
Target Protein:
Aromatase
Waktu ParuhThe elimination hal…
Vol. DistribusiThe volume of distr…
KlirensAnastrozole's clear…
Genetik -
Letrozole Approved DB01006
small molecule | CAS: 112809-51-5

Letrozole, or CGS 20267, is an oral non-steroidal type II aromatase inhibitor first described in the literature in 1990.[A190543,A1559,L11623,L11626] It is a third generation aromatase inhibitor like [exemestane] and [anastrozole], meaning it does not signifi…

Kategori:
Agents Causing Muscle ToxicityAntineoplastic AgentsAntineoplastic and Immunomodulating Agents +21
Target Protein:
Aromatase
Waktu ParuhThe terminal elimin…
Vol. DistribusiThe volume of distr…
KlirensThe average clearan…
Genetik -
Tamoxifen Approved DB00675
small molecule | CAS: 10540-29-1

Tamoxifen is a non-steroidal antiestrogen used to treat estrogen receptor positive breast cancers as well as prevent the incidence of breast cancer in high risk populations.[A1025,L7799,L7802] Tamoxifen is used alone or as an adjuvant in these treatments.[L77…

Kategori:
Anti-EstrogensAntineoplastic AgentsAntineoplastic Agents, Hormonal +64
Target Protein:
Estrogen receptorEstrogen receptor betaProtein kinase C +7
Gen Terkait:
CYP2D6 F5
Waktu ParuhThe terminal elimin…
Vol. DistribusiThe volume of distr…
KlirensThe clearance of ta…
Genetik 2 Varian