Hasil Filter

4

Total database: 17430
Struktur (SMILES)
4 (100.0%)
Target
3 (75.0%)
Genomik
0 (0%)
Referensi
4 (100.0%)

Tipe Molekul

Distribusi Wujud Zat

Status Regulasi

Hasil Pencarian (4)

Amcipatricin DB12333
small molecule | CAS: 143483-67-4

Amcipatricin has been used in trials studying the treatment of Cryptococcosis or Aspergillosis Infections. Amcipatricin (as amcipatricin diascorbate; SPK-843) is a water-soluble partricin derivative patented by SPA Societa Prodotti Antibiotici S.p.A. and deve…

Kategori:
AlkenesHydrocarbons, Acyclic
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Amphotericin B Approved DB00681
small molecule | CAS: 1397-89-3

Amphotericin B shows a high order of in vitro activity against many species of fungi. Histoplasma capsulatum, Coccidioides immitis, Candida species, Blastomyces dermatitidis, Rhodotorula, Cryptococcus neoformans, Sporothrix schenckii, Mucor mucedo, and Asperg…

Kategori:
Agents Causing Muscle ToxicityAgents that reduce seizure thresholdAlimentary Tract and Metabolism +30
Target Protein:
Ergosterol
Waktu ParuhAn elimination half…
Vol. Distribusi-
Klirens* 39 +/- 22 mL/hr/k…
Genetik -
Hydroxystilbamidine Approved DB14753
small molecule | CAS: 495-99-8

Hydroxystilbamidine isethionate is used in the therapy of some patients with nonprogressive blastomycosis of the skin, and pulmonary or systemic blastomycosis in children, with fewer side effects than amphotericin B. Hydroxystilbamidine isethionate is also us…

Kategori:
AmidinesBenzene DerivativesBenzylidene Compounds +1
Target Protein:
DNA
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Nystatin Approved DB00646
small molecule | CAS: 1400-61-9

Nystatin is a polyene antifungal drug that has broad-spectrum fungicidal and fungistatic activity against a number of yeasts and fungi, most notably _Candida_ species.[L10686] It is one of the most effective antifungal agents synthesized by bacteria, in this …

Kategori:
Alimentary Tract and MetabolismAnti-Infective AgentsAntidiarrheals, Intestinal Antiinflammatory/antiinfective Agents +17
Target Protein:
Ergosterol
Waktu Paruh-
Vol. DistribusiNystatin is not abs…
Klirens-
Genetik -