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Total database: 17430
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Hasil Pencarian (5)

Adefovir DB13868
small molecule | CAS: 106941-25-7

Deskripsi belum tersedia.

Kategori:
Anti-Infective AgentsAntiviral AgentsEnzyme Inhibitors +8
Target Protein:
Protein PDNA polymerase catalytic subunit
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Adefovir dipivoxil Approved DB00718
small molecule | CAS: 142340-99-6

Adefovir dipivoxil, previously called bis-POM PMEA, with trade names Preveon and Hepsera, is an orally-administered acyclic nucleotide analog reverse transcriptase inhibitor (ntRTI) used for treatment of hepatitis B. It is ineffective against HIV-1. Adefovir …

Kategori:
Anti-Infective AgentsAntiinfectives for Systemic UseAntiviral Agents +14
Target Protein:
Protein P
Waktu ParuhPlasma adefovir con…
Vol. Distribusi* 392 ± 75 mL/kg [V…
Klirens* 469 ± 99.0 mL/min…
Genetik -
Entecavir Approved DB00442
small molecule | CAS: 142217-69-4

Entecavir is an oral antiviral drug used in the treatment of hepatitis B infection. It is marketed under the trade name Baraclude (BMS). Entecavir is a guanine analogue that inhibits all three steps in the viral replication process, and the manufacturer cl…

Kategori:
Anti-Infective AgentsAntiinfectives for Systemic UseAntiviral Agents +12
Target Protein:
DNA
Waktu ParuhAfter reaching peak…
Vol. Distribusi-
Klirens* renal cl=383.2 +/…
Genetik -
Pradefovir DB15550
small molecule | CAS: 625095-60-5

Pradefovir is a prodrug of [adefovir].

Kategori:
Anti-Infective AgentsAnti-Retroviral AgentsAntiviral Agents +3
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 625095-61-6

Pradefovir mesilate (previously known as MB-06886, Hepavir B and remofovir mesylate) is an orally administered small molecule compound that belongs to a novel series of phosphate and phosphonate prodrugs of adefovir. [Adefovir] (Hepsera) is an acyclic phospho…

Kategori:
Anti-Infective AgentsAnti-Retroviral AgentsAntiviral Agents +3
Target Protein:
Cytochrome P450 3A4
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -