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Hasil Pencarian (4)

Adalimumab Approved DB00051
biotech | CAS: 331731-18-1

Adalimumab is a subcutaneously administered biological disease modifier for the treatment of rheumatoid arthritis and other chronic debilitating diseases mediated by tumor necrosis factor.[A39984,A39999] It was originally launched by Abbvie in the U.S. and ap…

Kategori:
Agents reducing cytokine levelsAmino Acids, Peptides, and ProteinsAnti-Inflammatory Agents +19
Target Protein:
Tumor necrosis factor
Waktu ParuhThe mean terminal h…
Vol. DistribusiThe distribution vo…
KlirensThe single-dose pha…
Genetik -
Bimekizumab Approved DB12917
biotech | CAS: 1418205-77-2

Bimekizumab is a humanized monoclonal antibody directed towards IL-17, which was approved for use in the EU on August 20, 2021, for the treatment of plaque psoriasis.[L39665,L39680] It is the first IL-17 inhibitor to target both IL-17A and IL-17F.[A244455] It…

Kategori:
Agents reducing cytokine levelsAmino Acids, Peptides, and ProteinsAntibodies +11
Target Protein:
Interleukin-17AInterleukin-17F
Waktu ParuhThe mean terminal e…
Vol. DistribusiIn patients with pl…
KlirensThe median apparent…
Genetik -
KT-A261 DB19317
biotech

KT-A261 is an adeno-associated viral vector serotype 2 (AAV2) encoded to express adalimumab. It is being investigated for the treatment of noninfectious uveitis.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Pateclizumab DB14997
biotech | CAS: 1202526-59-7

Pateclizumab is under investigation in clinical trial NCT01225393 (A Study to Evaluate the Efficacy and Safety of MLTA3698A in Combination With a Disease-Modifying Anti-Rheumatic Drug (DMARD) Compared With Adalimumab in Combination With a DMARD in Patients Wi…

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntibodies, Monoclonal +8
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -