Hasil Filter

5

Total database: 17430
Struktur (SMILES)
5 (100.0%)
Target
5 (100.0%)
Genomik
1 (20.0%)
Referensi
5 (100.0%)

Tipe Molekul

Distribusi Wujud Zat

Status Regulasi

Hasil Pencarian (5)

Acetylsalicylic acid Approved DB00945
small molecule | CAS: 50-78-2

Also known as _Aspirin_, acetylsalicylic acid (ASA) is a commonly used drug for the treatment of pain and fever due to various causes. Acetylsalicylic acid has both anti-inflammatory and antipyretic effects. This drug also inhibits platelet aggregation and i…

Kategori:
Acids, CarbocyclicAgents causing angioedemaAgents causing hyperkalemia +38
Target Protein:
Prostaglandin G/H synthase 13-hydroxy-3-methylglutaryl-coenzyme A reductaseProstaglandin G/H synthase 2 +17
Gen Terkait:
CYP2C9 ITGB3 LTC4S
Waktu ParuhThe half-life of AS…
Vol. DistribusiThis drug is distri…
KlirensThe clearance rate …
Genetik 3 Varian
Butalbital Approved DB00241
small molecule | CAS: 77-26-9

Butalbital, or 5-allyl-5-isobutylbarbituric acid, is a derivative of barbituric acid which the hydrogens at position 5 are substituted by an allyl group and an isobutyl group. It is a short-to-intermediate acting member of barbiturates that exhibit muscle-rel…

Kategori:
Anticholinergic AgentsAnticonvulsantsBarbiturates +12
Target Protein:
Gamma-aminobutyric acid receptor subunit alpha-2Gamma-aminobutyric acid receptor subunit alpha-3Gamma-aminobutyric acid receptor subunit alpha-4 +8
Waktu ParuhThe plasma half-lif…
Vol. DistribusiThe volume of distr…
KlirensThere is limited da…
Genetik -
Mesalazine Approved DB00244
small molecule | CAS: 89-57-6

An anti-inflammatory agent, structurally related to the salicylates and non-steroidal anti-inflammatory drugs like acetylsalicylic acid, which is active in inflammatory bowel disease [A174022]. Although demonstrably effective in treating and maintaining remis…

Kategori:
Agents causing hyperkalemiaAgents that produce hypertensionAminosalicylate +13
Target Protein:
Prostaglandin G/H synthase 2Prostaglandin G/H synthase 1Polyunsaturated fatty acid 5-lipoxygenase +4
Waktu ParuhFor the delayed-rel…
Vol. DistribusiFor the extended-re…
KlirensThe mean (SD) renal…
Genetik -
Methocarbamol Approved DB00423
small molecule | CAS: 532-03-6

Methocarbamol was developed in the early 1950s as a treatment for muscle spasticity and the associated pain.[A178441,A178450] It is a guaiacol glyceryl ether.[A178450] Methocarbamol tablets and intramuscular injections are prescription medicines indicated …

Kategori:
Acids, AcyclicBenzene DerivativesCarbamates +14
Target Protein:
Carbonic anhydrase 1
Waktu ParuhThe elimination hal…
Vol. DistribusiVolume of distribut…
Klirens0.2-0.8L/h/kg.[L626…
Genetik -
Sucralfate Approved DB00364
small molecule | CAS: 54182-58-0

Sucralfate is a medication that is widely used to prevent and treat a number of diseases in the gastrointestinal tract such as duodenal ulcers [FDA label], gastro-esophageal reflux disease (GERD), gastritis, peptic ulcer disease, stress ulcer, in addition to …

Kategori:
Alimentary Tract and MetabolismAluminium CompoundsAluminum Complex +14
Target Protein:
Pepsin A-5Fibroblast growth factor 2Pro-epidermal growth factor +1
Waktu ParuhThe half-life is no…
Vol. DistribusiThis drug is absorb…
KlirensSucralfate contains…
Genetik -