Hasil Filter

2

Total database: 17430
Struktur (SMILES)
0 (0%)
Target
1 (50.0%)
Genomik
0 (0%)
Referensi
2 (100.0%)

Tipe Molekul

Distribusi Wujud Zat

Status Regulasi

Hasil Pencarian (2)

Zanidatamab Approved DB15471
biotech | CAS: 2169946-15-8

Zanidatamab is a bispecific antibody that binds two non-overlapping sites of HER2 (ERBB2).[A264718] It has been investigated for the treatment of HER2-positive solid tumors, including gastroesophageal, colorectal, and biliary tract cancers.[A264718] In No…

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntibodies, Monoclonal +9
Target Protein:
Receptor tyrosine-protein kinase erbB-2
Waktu ParuhBased on population…
Vol. DistribusiBased on population…
KlirensBased on population…
Genetik -
biotech | CAS: 2329698-82-8

According to Zymeworks, "ZW49 (zanidatamab zovodotin) is a bispecific anti-HER2 ADC that is based on the same antibody framework as [ZW25] but armed with a cytotoxic payload."[L8234] It is being investigated for several indications characterized by HER2 expre…

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -