Hasil Pencarian (2)
Bamocaftor
DB15177
small molecule | CAS: 2204245-48-5
Bamocaftor (VX-659) is under investigation in clinical trial NCT03224351 (A Study Evaluating the Safety and Efficacy of VX-659 Combination Therapy in Subjects With Cystic Fibrosis).
Kategori:
Chloride Channel AgonistsMembrane Transport Modulators
Waktu Paruh-
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Genetik
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small molecule | CAS: 2216712-66-0
Elexacaftor (previously VX-445) is a small molecule, next-generation corrector of the cystic fibrosis transmembrane conductance regulator (CFTR) protein.[A187361] It received FDA approval in October 2019 in combination with [tezacaftor] and [ivacaftor] as the…
Kategori:
Cystic Fibrosis Transmembrane Conductance Regulator CorrectorsCytochrome P-450 CYP1A2 InhibitorsCytochrome P-450 CYP1A2 Inhibitors (strength unknown)
+24
Target Protein:
Cystic fibrosis transmembrane conductance regulator
Waktu ParuhThe mean terminal h…
Vol. DistribusiThe apparent volume…
KlirensThe mean apparent c…
Genetik
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