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11

Total database: 17430
Struktur (SMILES)
10 (90.9%)
Target
7 (63.6%)
Genomik
1 (9.1%)
Referensi
11 (100.0%)

Tipe Molekul

Distribusi Wujud Zat

Status Regulasi

Hasil Pencarian (11)

3-Allylfentanyl DB09169
small molecule | CAS: 82208-84-2

3-allyfentanyl is a fentanyl derivative opioid that can cause itching, nausea and serious respiratory depression. Fentanyl and its analogs have killed thousands of people around the world as drugs of abuse.

Kategori:
Piperidines
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Albuterol Approved DB01001
small molecule | CAS: 18559-94-9

Salbutamol (Albuterol [USAN]) is a short-acting, selective beta2-adrenergic receptor agonist used in the treatment of asthma and COPD. It is 29 times more selective for beta2 receptors than beta1 receptors giving it higher specificity for pulmonary beta recep…

Kategori:
Adrenergic AgentsAdrenergic AgonistsAdrenergic beta-2 Receptor Agonists +27
Target Protein:
Beta-2 adrenergic receptorBeta-1 adrenergic receptorBeta-3 adrenergic receptor
Waktu ParuhThe elimination hal…
Vol. DistribusiThe volume of distr…
KlirensThe renal clearance…
Genetik -
Calcipotriol Approved DB02300
small molecule | CAS: 112965-21-6

Calcipotriol (INN) or calcipotriene (USAN) is a sythetic derivative of calcitriol or Vitamin D.

Kategori:
AntipsoriaticsAntipsoriatics for Topical UseCholestanes +12
Target Protein:
Vitamin D3 receptor
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Dosulepin Approved DB09167
small molecule | CAS: 113-53-1

Dosulepin (INN, BAN) formerly known as dothiepin (USAN), is a tricyclic antidepressant with anxiolytic properties that is used in several European and South Asian countries, as well as Australia, South Africa, and New Zealand. It is not FDA-approved due to lo…

Kategori:
Adrenergic AgentsAdrenergic Uptake InhibitorsAgents producing tachycardia +45
Target Protein:
5-hydroxytryptamine receptor 1A5-hydroxytryptamine receptor 2AHistamine H1 receptor +9
Waktu ParuhThe elimination hal…
Vol. DistribusiThe mean apparent V…
KlirensOral clearance is a…
Genetik -
Etamivan DB08989
small molecule | CAS: 304-84-7

Etamivan (INN) or ethamivan (USAN) is marketed under the name Analepticon. Etamvin is a respiratory stimulant drug similar to nikethamide. It is no longer used in the United States.

Kategori:
Acids, CarbocyclicAmidesBenzene Derivatives +2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Fluclorolone acetonide Approved DB08973
small molecule | CAS: 3693-39-8

Fluclorolone acetonide (INN) or flucloronide (USAN) is a topical corticosteroid. It is marketed under the brand names Cutanit and Topicon.

Kategori:
Adrenal Cortex HormonesCorticosteroidsFused-Ring Compounds +3
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Imidacloprid DB11421
small molecule | CAS: 105827-78-9

Imidacloprid is a neonicotinoid, which is a class of neuro-active insecticides modeled after nicotine. Imidacloprid is a patented chemical, Imidacloprid is manufactured by Bayer Cropscience (part of Bayer AG) and sold under trade names Kohinor, Admire, Advant…

Kategori:
AgrochemicalsCholinergic AgentsCompounds used in a research, industrial, or household setting +4
Target Protein:
CHRNA7-FAM7A fusion protein
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Metocurine Approved DB01336
small molecule | CAS: 5152-30-7

Dimethyltubocurarinium (INN) or metocurine (USAN), also known as dimethyltubocurarine, is a non-depolarizing muscle relaxant. Patients on chronic anticonvulsant drugs are relatively resistant to metocurine. [A2393]

Kategori:
Agents producing tachycardiaAlkaloidsAmines +18
Target Protein:
Neuronal acetylcholine receptor subunit alpha-2Muscarinic acetylcholine receptor M2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Mitoquinone DB05063
small molecule | CAS: 444890-41-9

Mitoquinone is based on a novel technology, targeted lipophilic cations, that transport and concentrate antioxidants into the mitochondria -- organelles inside cells that provide energy for life processes -- where they accumulate up to a thousand fold. In 200…

Kategori:
BenzoquinonesCoenzymesEnzymes and Coenzymes +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Opium Approved DB11130
small molecule | CAS: 8008-60-4

Opium is the first substance of the diverse group of the opiates. It has been known for a long time, and the first evidence of a poppy culture dates from 5 thousand years by the Sumerians. During the years, opium was used as a sedative and hypnotic, but it wa…

Kategori:
Alimentary Tract and MetabolismAnalgesicsAntidiarrheals +25
Target Protein:
Delta-type opioid receptorKappa-type opioid receptorMu-type opioid receptor
Waktu ParuhThe half-life of op…
Vol. DistribusiOpium presents a la…
Klirens-
Genetik -
Tegafur Approved DB09256
small molecule | CAS: 17902-23-7

Tegafur (INN, BAN, USAN) is a prodrug of [DB00544] (5-FU), an antineoplastic agent used as the treatment of various cancers such as advanced gastric and colorectal cancers. It is a pyrimidine analogue used in combination therapies as an active chemotherapeuti…

Kategori:
AntimetabolitesAntineoplastic AgentsAntineoplastic and Immunomodulating Agents +22
Target Protein:
Thymidylate synthase
Gen Terkait:
DPYD DPYD DPYD +4
Waktu ParuhThe elimination hal…
Vol. DistribusiThe volume of distr…
KlirensNo pharmacokinetic …
Genetik 7 Varian