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Total database: 17430
Struktur (SMILES)
1 (33.3%)
Target
3 (100.0%)
Genomik
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Referensi
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Hasil Pencarian (3)

Arotinolol DB09204
small molecule | CAS: 68377-92-4

Arotinolol is an alpha- and beta-receptor blocker developed in Japan. It is a thiopropanolamine with a tertiary butyl moiety. It has been studied for its potential to be an antihypertensive therapy.[T87] Artinolol is being developed by Sumitomo Pharmaceutical…

Kategori:
Adrenergic AgentsAdrenergic AntagonistsAdrenergic beta-Antagonists +11
Target Protein:
Beta-1 adrenergic receptorBeta-2 adrenergic receptorAlpha-1 adrenergic receptors
Waktu ParuhThe reported half-l…
Vol. DistribusiThe stereospecifici…
Klirens-
Genetik -
Betibeglogene autotemcel Approved DB16900
biotech

Betibeglogene autotemcel is an autologous gene therapy that adds functional copies of the ?-globin gene (?<sup>A-T87Q</sup>-globin) to hematopoietic stem cells in order to treat ?-thalassemia.[L42940] ?-thalassemia is a condition caused by mutations in the ?-…

Kategori:
Autologous Cultured CellAutologous Hematopoietic Stem Cell-Based Gene TherapyBlood and Blood Forming Organs +2
Target Protein:
Alpha globin
Waktu Paruh-
Vol. DistribusiThe nature of betib…
Klirens-
Genetik -
Lovotibeglogene autotemcel Approved DB18680
biotech

Lovotibeglogene autotemcel consists of autologous hematopoietic stem and progenitor cells transduced with the BB305 lentiviral vector encoding a modified ?-globin gene. Specifically, lovotibeglogene autotemcel provides a functional copy of a modified beta-glo…

Kategori:
Autologous Cultured CellAutologous Hematopoietic Stem Cell-Based Gene TherapyGenetic Therapy
Target Protein:
Hemoglobin subunit beta
Waktu ParuhLovotibeglogene aut…
Vol. DistribusiLovotibeglogene aut…
KlirensLovotibeglogene aut…
Genetik -