Hasil Pencarian (2)
biotech | CAS: 1690318-25-2
Crizanlizumab is a humanized IgG2 monoclonal antibody used to reduce the frequency of vaso-occlusive crises in patients with sickle cell disease.[L10097] Sickle cell disease is a genetically inherited condition prevalent in the Middle East, Africa, and certai…
Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntibodies, Monoclonal
+10
Target Protein:
P-selectin
Waktu ParuhGiven a 5mg/kg dose…
Vol. DistribusiThe volume of distr…
KlirensGiven a 5mg/kg dose…
Genetik
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small molecule | CAS: 1446321-46-5
Voxelotor is a novel hemoglobin S polymerization inhibitor for the treatment of sickle cell disease. This is a genetically inherited condition most prevalent in the Middle East, Africa, and certain parts of India. Sickle cell disease can lead to excruciating …
Kategori:
AldehydesBlood and Blood Forming OrgansCytochrome P-450 CYP2B6 Substrates
+7
Target Protein:
Hemoglobin subunit alpha
Waktu ParuhThe plasma eliminat…
Vol. DistribusiThe apparent volume…
KlirensThe apparent oral c…
Genetik
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