Hasil Filter

3

Total database: 17430
Struktur (SMILES)
3 (100.0%)
Target
2 (66.7%)
Genomik
0 (0%)
Referensi
3 (100.0%)

Tipe Molekul

Distribusi Wujud Zat

Status Regulasi

Hasil Pencarian (3)

Colfosceril palmitate Approved DB09114
small molecule | CAS: 63-89-8

Colfosceril palmitate is a synthetic pulmonary surfactant administered in infants with respiratory distress syndrome.[A31510] It was part of the first generation of commercially available artificial surfactants.[T70] It was developed by Burroughs Wellcome and…

Kategori:
GlycerophosphatesGlycerophospholipidsLipids +6
Waktu ParuhThe half-life of co…
Vol. DistribusiColfosceril palmita…
KlirensAfter 5 days of dru…
Genetik -
Samuraciclib DB16061
small molecule | CAS: 1805833-75-3

Samuraciclib is under investigation in clinical trial NCT03363893 (Modular Study to Evaluate CT7001 Alone in Cancer Patients With Advanced Malignancies).

Target Protein:
Cyclin-dependent kinase 7
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Trimethoprim Approved DB00440
small molecule | CAS: 738-70-5

Trimethoprim is an antifolate antibacterial agent that inhibits bacterial dihydrofolate reductase (DHFR), a critical enzyme that catalyzes the formation of tetrahydrofolic acid (THF) - in doing so, it prevents the synthesis of bacterial DNA and ultimately con…

Kategori:
Agents causing hyperkalemiaAgents Causing Muscle ToxicityAnti-Infective Agents +32
Target Protein:
Dihydrofolate reductaseDihydrofolate reductase
Waktu ParuhTrimethoprim half-l…
Vol. DistribusiTrimethoprim is ext…
KlirensFollowing oral admi…
Genetik -