Hasil Pencarian (2)
small molecule | CAS: 51384-51-1
Metoprolol is a selective beta-1 blocker commonly employed as the succinate and tartrate derivatives depending if the formulation is designed to be of immediate release or extended release.[A175159, L5530] The possibility of the generation of these formulatio…
Kategori:
Adrenergic AgentsAdrenergic AntagonistsAdrenergic beta-1 Receptor Antagonists
+29
Target Protein:
Beta-1 adrenergic receptorBeta-2 adrenergic receptorBeta adrenergic receptor
Gen Terkait:
ADRB1
CYP2D6
ADRB1
Waktu ParuhThe immediate relea…
Vol. DistribusiThe reported volume…
KlirensThe reported cleara…
Genetik
3 Varian
small molecule | CAS: 81093-37-0
Pravastatin is the 6-alpha-hydroxy acid form of [mevastatin].[T303] Pravastatin was firstly approved in 1991 becoming the second available statin in the United States. It was the first statin administered as the active form and not as a prodrug.[T274] This dr…
Kategori:
Agents Causing Muscle ToxicityAnticholesteremic AgentsBCRP/ABCG2 Inhibitors
+20
Target Protein:
3-hydroxy-3-methylglutaryl-coenzyme A reductaseHistone deacetylase 2
Gen Terkait:
KIF6
HMGCR
Waktu ParuhThe reported elimin…
Vol. DistribusiThe reported steady…
KlirensThe reported cleara…
Genetik
2 Varian