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Lofexidine Approved DB04948
small molecule | CAS: 31036-80-3

Lofexidine is a non-opioid centrally acting alpha2-adrenergic receptor agonist that was first approved for the treatment of opioid withdrawal in the United Kingdom in 1992.[A33084] It was first studied for use as an antihypertensive in 1980, but its researche…

Kategori:
Adrenergic AgentsAdrenergic AgonistsAdrenergic alpha-2 Receptor Agonists +31
Target Protein:
Alpha-2A adrenergic receptorAlpha-1A adrenergic receptor5-hydroxytryptamine receptor 1A +3
Waktu ParuhThe reported elimin…
Vol. DistribusiLofexidine has a vo…
KlirensThe total eliminati…
Genetik -