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Total database: 17430
Struktur (SMILES)
5 (100.0%)
Target
3 (60.0%)
Genomik
0 (0%)
Referensi
5 (100.0%)

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Distribusi Wujud Zat

Status Regulasi

Hasil Pencarian (5)

L-Octahydroindole-2-carboxylic acid DB03409
small molecule | CAS: 80875-98-5

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Olmesartan Approved DB00275
small molecule | CAS: 144689-24-7

Olmesartan belongs to the angiotensin II receptor blocker (ARB) family of drugs, which also includes [telmisartan], [candesartan], [losartan], [valsartan], and [irbesartan]. ARBs selectively bind to angiotensin receptor 1 (AT1) and prevent the protein angiote…

Kategori:
Agents Acting on the Renin-Angiotensin SystemAgents causing hyperkalemiaAngiotensin 2 Receptor Blocker +15
Target Protein:
Type-1 angiotensin II receptor
Waktu ParuhThe mean plasma olm…
Vol. Distribusi17 L[L5566]
KlirensTotal plasma cleara…
Genetik -
Perindopril Approved DB00790
small molecule | CAS: 82834-16-0

Perindopril is a nonsulfhydryl prodrug that belongs to the angiotensin-converting enzyme (ACE) inhibitor class of medications. It is rapidly metabolized in the liver to perindoprilat, its active metabolite, following oral administration. Perindoprilat is a po…

Kategori:
ACE Inhibitors and Calcium Channel BlockersACE Inhibitors and DiureticsAgents Acting on the Renin-Angiotensin System +18
Target Protein:
Angiotensin-converting enzymeSecreted frizzled-related protein 4
Waktu ParuhPerindopril, 1.2 ho…
Vol. Distribusi-
Klirens* 219 - 362 mL/min …
Genetik -
Perindoprilat DB14213
small molecule | CAS: 95153-31-4

The active metabolite of the prodrug [Perindopril].

Kategori:
Agents Acting on the Renin-Angiotensin SystemAgents causing angioedemaAgents causing hyperkalemia +6
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Valsartan Approved DB00177
small molecule | CAS: 137862-53-4

Valsartan belongs to the angiotensin II receptor blocker (ARB) family of drugs, which also includes [telmisartan], [candesartan], [losartan], [olmesartan], and [irbesartan]. ARBs selectively bind to angiotensin receptor 1 (AT1) and prevent the protein angiote…

Kategori:
Agents Acting on the Renin-Angiotensin SystemAgents causing angioedemaAgents causing hyperkalemia +22
Target Protein:
Type-1 angiotensin II receptor
Waktu ParuhAfter intravenous (…
Vol. DistribusiThe steady-state vo…
KlirensFollowing intraveno…
Genetik -