Hasil Pencarian (2)
small molecule | CAS: 2628280-40-8
Nirmatrelvir (PF-07321332) is an orally bioavailable 3C-like protease (3CL<sup>PRO</sup>) inhibitor that is the subject of clinical trial NCT04756531.[L33354] 3CL<sup>PRO</sup> is responsible for cleaving polyproteins 1a and 1ab of SARS-CoV-2.[A234224] Withou…
Kategori:
AmidesAmino AcidsAmino Acids, Branched-Chain
+22
Target Protein:
Replicase polyprotein 1ab
Waktu ParuhThe mean half-life …
Vol. DistribusiThe mean volume of …
KlirensThe mean oral clear…
Genetik
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PF-07304814
DB16514
small molecule
PF-07304814 is a small molecule prodrug that targets the 3CL<sup>pro</sup> protease (M<sup>pro)</sup>, which is used by viruses like SARS-CoV-2 to assemble and multiply[L31718]. Once administered through intravenous infusion, the compound is cleaved into PF-0…
Kategori:
Amino AcidsAmino Acids, Branched-ChainAmino Acids, Essential
+4
Target Protein:
Replicase polyprotein 1ab
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik
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