Hasil Pencarian (2)
small molecule | CAS: 120014-06-4
In 2016, the global burden of dementia was estimated to be 43.8 million, demonstrating a significant increase from a global prevalence of 20.2 million in 1990.[A182411] Donepezil, also known as Aricept, is a piperidine derivative acetylcholinesterase inhibito…
Kategori:
Anti-Dementia DrugsBCRP/ABCG2 SubstratesBradycardia-Causing Agents
+20
Target Protein:
Acetylcholinesterase5-hydroxytryptamine receptor 2ACholinesterase
+5
Gen Terkait:
CYP2D6
Waktu ParuhThe average elimina…
Vol. DistribusiThe volume of distr…
KlirensAccording to the FD…
Genetik
1 Varian
small molecule | CAS: 19982-08-2
Initially approved by the FDA in 2013, memantine is an N-methyl-D-aspartate (NMDA) receptor antagonist used in the management of Alzheimer's Disease (AD). It is different from many other Alzheimer's Disease medications, as it works by a different mechanism t…
Kategori:
Anti-Dementia DrugsAnti-Dyskinesia AgentsAnti-Parkinson Drugs
+20
Target Protein:
Glutamate (NMDA) receptor5-hydroxytryptamine receptor 3ANeuronal acetylcholine receptor subunit alpha-7
+3
Waktu ParuhThe terminal elimin…
Vol. DistribusiThe mean volume of …
KlirensThis drug is cleare…
Genetik
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