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4

Total database: 17430
Struktur (SMILES)
4 (100.0%)
Target
4 (100.0%)
Genomik
0 (0%)
Referensi
4 (100.0%)

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Distribusi Wujud Zat

Status Regulasi

Hasil Pencarian (4)

Hydroxyprogesterone caproate Approved DB06789
small molecule | CAS: 630-56-8

Hydroxyprogesterone caproate is a synthetic steroid hormone that is similar to medroxyprogesterone acetate and megestrol acetate. It is an ester derivative of 17?-hydroxyprogesterone formed from caproic acid (hexanoic acid). Hydroxyprogesterone caproate was p…

Kategori:
Adrenal Cortex HormonesAntineoplastic AgentsCombination Contraceptives (with Estrogen and derivatives) +26
Target Protein:
Progesterone receptor
Waktu ParuhHalf-life = 16 days…
Vol. DistribusiHydroxyprogesterone…
KlirensClearance is highly…
Genetik -
Megestrol acetate Approved DB00351
small molecule | CAS: 595-33-5

17-Hydroxy-6-methylpregna-3,6-diene-3,20-dione. A progestational hormone used most commonly as the acetate ester. As the acetate, it is more potent than progesterone both as a progestagen and as an ovulation inhibitor. It has also been used in the palliative …

Kategori:
Adrenal Cortex HormonesAntineoplastic AgentsAntineoplastic Agents, Hormonal +31
Target Protein:
Progesterone receptorGlucocorticoid receptor
Waktu Paruh34 hours
Vol. Distribusi-
Klirens-
Genetik -
Nomegestrol acetate Approved DB13981
small molecule | CAS: 58652-20-3

Nomegestrol acetate, also known as NOMAC, is a progestin used in oral contraceptives, menopausal hormone therapy, and for the treatment of gynecological disorders.

Kategori:
Adrenal Cortex HormonesCombination Contraceptives (with Estrogen and derivatives)Contraceptive Agents, Female +14
Target Protein:
Estrogen receptor
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Progesterone Approved DB00396
small molecule | CAS: 57-83-0

Progesterone is a hormone that occurs naturally in females, and is essential for endometrial receptivity, embryo implantation, and the successful establishment of pregnancy. A low progesterone concentration or an insufficient response to progesterone can caus…

Kategori:
Adrenal Cortex HormonesBCRP/ABCG2 InducersBCRP/ABCG2 Inhibitors +47
Target Protein:
Progesterone receptorMineralocorticoid receptorEstrogen receptor +7
Waktu ParuhAbsorption half-lif…
Vol. DistribusiWhen administered v…
Klirens**Apparent clearanc…
Genetik -