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Total database: 17430
Struktur (SMILES)
41 (87.2%)
Target
14 (29.8%)
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Hasil Pencarian (47)

small molecule | CAS: 36330-79-7

Deskripsi belum tersedia.

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Almasilate Approved DB13595
small molecule | CAS: 71205-22-6

Almasilate is a buffering antacid that has been used in peptic ulcers and dyspepsia. It is a crystalline polyhydrate of aluminium/magnesium silicate and mediates its buffering activity by binding hydrogen ions within the polymer. However its therapeutic effic…

Kategori:
Alimentary Tract and MetabolismAluminum and magnesium containing antacidsAntacids +6
Waktu ParuhReadily accessible …
Vol. DistribusiThe distribution of…
KlirensReadily accessible …
Genetik -
Ascorbyl phosphate Approved DB11352
small molecule

Ascorbyl phosphate is a synthetic form of Vitamin C and is found in different salt forms such as magnesium ascorbyl phosphate and sodium ascorbyl phosphate. These salts are present in cosmetic products at concentrations ranging from 0.001 % to 3% [A27211]. As…

Kategori:
Acids, AcyclicCarbohydratesHydroxy Acids +3
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Attapulgite Approved DB01574
small molecule | CAS: 12174-11-7

Attapulgite is a magnesium aluminium phyllosilicate which occurs in a type of clay soil common to the Southeastern United States. When used in medicine, it physically binds to acids and toxic substances in the stomach and digestive tract. For that reason, it …

Kategori:
Alimentary Tract and MetabolismAntidiarrheals, Intestinal Antiinflammatory/antiinfective AgentsAntidotes +3
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small molecule | CAS: 1224727-39-2

Deskripsi belum tersedia.

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small molecule | CAS: 64425-90-7

Choline magnesium trisalicylate is a non-acetylated salicylate used widely as a nonsteroidal anti-inflammatory drug. Trisalicylate significantly reduces methotrexate renal clearance, displacing methotrexate from protein, increasing the fraction unbound by 28%…

Kategori:
Acids, CarbocyclicAgents causing hyperkalemiaAgents that produce hypertension +23
Target Protein:
Prostaglandin G/H synthase 1Prostaglandin G/H synthase 2
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Citric acid Approved DB04272
small molecule | CAS: 77-92-9

A key intermediate in metabolism. It is an acid compound found in citrus fruits. The salts of citric acid (citrates) can be used as anticoagulants due to their calcium-chelating ability. Citric acid is one of the active ingredients in Phexxi, a non-hormona…

Kategori:
Acid PreparationsAcidifying ActivityAcids, Acyclic +16
Target Protein:
Metallo-beta-lactamase type 2Lanosterol 14-alpha demethylaseTransient receptor potential cation channel subfamily V member 4 +49
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Desoxyribonuclease Approved DB09551
biotech | CAS: 9003-98-9

Desoxyribonuclease is a crystalline enzyme that aids in the digestion of the thymus nucleic acid. The mechanism of action of the enzyme involves the splitting of thymus nucleic acid into fragments approaching the size of tetranucleotides without the release o…

Kategori:
Blood and Blood Forming OrgansDeoxyribonucleasesEnzymes +3
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Magaldrate Approved DB08938
small molecule | CAS: 74978-16-8

Magaldrate is an antacid drug used for the treatment of esophagitis, duodenal and gastric ulcers, and gastroesophageal reflux. Magaldrate has been discontinued in the US market.

Kategori:
Alimentary Tract and MetabolismAlkaliesAluminium Compounds +13
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Magnesium Approved DB14513
small molecule | CAS: 7439-95-4

Magnesium is classified as an alkaline earth metal and has 2 hydration shells.[A19349] The element can be found in abundance in the hydrosphere and in mineral salts such as dolomite and magnesium carbonate.[A19349] Common dietary sources of magnesium incl…

Kategori:
ElementsLaxativesMagnesium Compounds +6
Waktu ParuhMagnesiums biologic…
Vol. DistribusiAccording to a phar…
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Magnesium acetate Approved DB13996
small molecule | CAS: 142-72-3

Deskripsi belum tersedia.

Kategori:
Acids, AcyclicAgents that produce neuromuscular block (indirect)Fatty Acids +3
Target Protein:
Sodium/potassium-transporting ATPase subunit alpha-1
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small molecule | CAS: 16674-78-5

Magnesium acetate tetrahydrate is a hydrated form of anhydrous magnesium acetate salt with the chemical formula of Mg(CH3COO)2 • 4H2O. As a salt form of magnesium, magnesium acetate is one of the bioavailable forms of magnesium and forms a very water soluble …

Kategori:
Agents that produce neuromuscular block (indirect)Laxatives
Target Protein:
Glutamate (NMDA) receptor
Waktu ParuhElimination half-li…
Vol. DistribusiMagnesium ions disp…
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Magnesium Aluminum Silicate Approved DB11230
small molecule | CAS: 1327-43-1

Magnesium aluminum silicate is a naturally occurring mineral obtained from silicate ores of the montmorillonite group [A32782]. It is refined to a powder for use in cosmetic and pharmaceutical applications as an absorbent, anticaking agent, opacifying agent, …

Kategori:
Agents that produce neuromuscular block (indirect)MineralsPharmaceutic Aids +1
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Magnesium ascorbate Approved DB14484
small molecule | CAS: 15431-40-0

Deskripsi belum tersedia.

Kategori:
Acids, AcyclicAntioxidantsBiological Factors +10
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small molecule | CAS: 7018-07-7

Magnesium aspartate is a magnesium salt of aspartic acid that is commonly used as a mineral supplement. It displays high oral bioavailability and water solubiltiy compared to other magnesium salts such as magnesium citrate, magnesium carbonate and magnesium o…

Kategori:
Agents that produce neuromuscular block (indirect)Alimentary Tract and MetabolismAmino Acids +8
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small molecule | CAS: 28184-71-6

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Magnesium carbonate Approved DB09481
small molecule | CAS: 546-93-0

Magnesium carbonate, also known as magnesite, is a common over the counter remedy for heartburn and upset stomach caused by overproduction of acid in the stomach [FDA Label].

Kategori:
Agents that produce neuromuscular block (indirect)Alimentary Tract and MetabolismAluminum and magnesium containing antacids +20
Target Protein:
Glutamate (NMDA) receptor
Waktu ParuhHalf life of 27.7 h…
Vol. DistribusiVd for magnesium is…
KlirensMaximum magnesium c…
Genetik -
Magnesium cation Approved DB01378
small molecule | CAS: 22537-22-0

Magnesium hydroxide is used primarily in "Milk of Magnesia", a white aqueous, mildly alkaline suspension of magnesium hydroxide formulated at about 8%w/v. Milk of magnesia is primarily used to alleviate constipation, but can also be used to relieve indigestio…

Kategori:
Agents that produce neuromuscular block (indirect)Calculi Dissolution AgentIncreased Large Intestinal Motility +9
Target Protein:
Sodium/potassium-transporting ATPase subunit alpha-1
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Magnesium chloride Approved DB09407
small molecule | CAS: 7786-30-3

Magnesium chloride salts are highly soluble in water and the hydrated form of magnesium chloride can be extracted from brine or sea water.

Kategori:
Agents that produce neuromuscular block (indirect)Alimentary Tract and MetabolismBlood and Blood Forming Organs +12
Waktu ParuhElimination half-li…
Vol. DistribusiBone (50% to 60%); …
KlirensMaximum magnesium c…
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Magnesium citrate Approved DB11110
small molecule | CAS: 3344-18-1

Magnesium citrate is a low volume and osmotic cathartic agent. The cathartic action works primarily through the high osmolarity of the solution which draws large amounts of fluid into space where is used.[T215] Magnesium citrate is considered by the FDA as an…

Kategori:
Acids, AcyclicAgents that produce neuromuscular block (indirect)Alimentary Tract and Metabolism +15
Waktu ParuhThe study of the ha…
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Magnesium gluconate Approved DB13749
small molecule | CAS: 59625-89-7

Magnesium gluconate is a magnesium salt of gluconate. It demonstrates the highest oral bioavailability of magnesium salts [L2608] and is used as a mineral supplement. Magnesium is ubiquitous in the human body, and is naturally present in many foods, added to …

Kategori:
Acids, AcyclicAgents that produce neuromuscular block (indirect)Alimentary Tract and Metabolism +7
Waktu Paruh-
Vol. DistribusiAbout 60% of the ma…
KlirensThe kidney plays a …
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Magnesium glycinate Approved DB11189
small molecule | CAS: 14783-68-7

Magnesium glycinate is a magnesium salt of glycine that is available as dietary supplements as a source of magnesium. It is used in the treatment of magnesium deficiency.

Kategori:
Agents that produce neuromuscular block (indirect)Laxatives
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Magnesium hydroxide Approved DB09104
small molecule | CAS: 1309-42-8

Magnesium hydroxide is an inorganic compound. It is naturally found as the mineral brucite. Magnesium hydroxide can be used as an antacid or a laxative in either an oral liquid suspension or chewable tablet form. Additionally, magnesium hydroxide has smoke …

Kategori:
Agents that produce neuromuscular block (indirect)Alimentary Tract and MetabolismAlkalies +22
Waktu ParuhN/A
Vol. DistribusiThe peak action and…
KlirensMagnesium hydroxide…
Genetik -
small molecule | CAS: 18917-93-6

Deskripsi belum tersedia.

Kategori:
Alimentary Tract and MetabolismMagnesium CompoundsMetal cations +2
Target Protein:
Sodium/potassium-transporting ATPase subunit alpha-1
Waktu Paruh-
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small molecule | CAS: 58505-81-0

Deskripsi belum tersedia.

Kategori:
Alimentary Tract and MetabolismEnzyme InhibitorsKeto Acids +4
Target Protein:
Sodium/potassium-transporting ATPase subunit alpha-1
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Magnesium malate Approved DB15555
small molecule | CAS: 869-06-7

Deskripsi belum tersedia.

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small molecule | CAS: 83918-60-9

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small molecule | CAS: 34717-03-8

Magnesium orotate is a magnesium salt of orotic acid and is poorly soluble in water. It is a source of magnesium and is used as a mineral supplement to treat Mg deficiency. Orotic acid acts as a transporter that carries magnesium into the cells. It also exhib…

Kategori:
Agents that produce neuromuscular block (indirect)Alimentary Tract and MetabolismMagnesium Compounds +5
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Magnesium oxide Approved DB01377
small molecule | CAS: 1309-48-4

Magnesium oxide is an inorganic compound that occurs in nature as the mineral periclase. In aqueous media combines quickly with water to form magnesium hydroxide. It is used as an antacid and mild laxative and has many nonmedicinal uses.

Kategori:
Agents that produce neuromuscular block (indirect)Alimentary Tract and MetabolismAluminum and magnesium containing antacids +16
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small molecule | CAS: 14452-57-4

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Kategori:
Alimentary Tract and MetabolismAluminum and magnesium containing antacidsAnions +15
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small molecule | CAS: 7757-87-1

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Kategori:
AcidsAcids, NoncarboxylicAgents that produce neuromuscular block (indirect) +10
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small molecule | CAS: 18917-89-0

Magnesium salicylate is a non-steroidal anti-inflammatory drug (NSAID) used to treat mild to moderate pain. It is available in several over-the-counter (OTC) formulations. Though the recommended doseage is 1160 mg every six hours, per package directions of th…

Kategori:
Acids, CarbocyclicAgents causing hyperkalemiaAgents that produce hypertension +23
Target Protein:
Prostaglandin G/H synthase 2Prostaglandin G/H synthase 1
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Magnesium silicate Approved DB13249
small molecule | CAS: 1343-88-0

Magnesium silicate is a compound of magnesium oxide and silicon. It is the magnesium salt of silicic acid containing an unspecified amount of water. The molecular formula can be expressed more clearly as MgSiO3.xH2O.[T186] It is known as talc and it presents …

Kategori:
Agents that produce neuromuscular block (indirect)Alimentary Tract and MetabolismAluminum and magnesium containing antacids +9
Waktu ParuhThe very low absorp…
Vol. DistribusiThe very low absorp…
KlirensThe very low absorp…
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small molecule | CAS: 557-04-0

Deskripsi belum tersedia.

Kategori:
Agents that produce neuromuscular block (indirect)Fatty AcidsLipids
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Magnesium sulfate Approved DB00653
small molecule | CAS: 7487-88-9

A small colorless crystal used as an anticonvulsant, a cathartic, and an electrolyte replenisher in the treatment of pre-eclampsia and eclampsia. It causes direct inhibition of action potentials in myometrial muscle cells. Excitation and contraction are uncou…

Kategori:
Agents causing hyperkalemiaAgents that produce neuromuscular block (indirect)Alimentary Tract and Metabolism +38
Target Protein:
Voltage-dependent L-type calcium channel
Waktu Paruh43.2 hours (for new…
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Magnesium trisilicate Approved DB09281
small molecule | CAS: 14987-04-3

Magnesium trisilicate is an inorganic compound that is used as an antacid in the treatment of peptic ulcers.

Kategori:
Agents that produce neuromuscular block (indirect)Aluminum and magnesium containing antacidsAntacids +10
Waktu Paruh16-20 hours
Vol. DistribusiThe hydrated silico…
KlirensMaximum magnesium c…
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small molecule | CAS: 3616-04-4

Calcium and magnesium salts used therapeutically in hepatobiliary dysfunction.

Kategori:
AminesOnium CompoundsPhosphorylcholine +2
Target Protein:
C-reactive proteinEpididymal sperm-binding protein 1Gamma-hemolysin component B
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Picosulfuric acid Approved DB09268
small molecule | CAS: 10040-34-3

Picosulfuric acid is found in laxative products. Sodium picosulfate is a used to treat constipation or induce colon cleansing to prepare the large bowels before colonoscopy or surgery. The combination product containing sodium picosulfate and magnesium citrat…

Kategori:
Acids, AcyclicAlimentary Tract and MetabolismContact Laxatives +6
Waktu ParuhThe terminal half-l…
Vol. DistribusiNot available.
KlirensNot available.
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Potassium Approved DB14500
small molecule | CAS: 7440-09-7

Potassium is an essential nutrient, like [Calcium] and [Magnesium]. It was identified as a shortfall nutrient by the 2015-2020 Advisory Committee of Dietary Guidelines for Americans.[A186928] Many conditions and diseases interfere with normal body potassium b…

Kategori:
Agents causing hyperkalemiaDiureticsElements +8
Target Protein:
Sodium/potassium-transporting ATPase subunit alpha-1
Waktu ParuhIn one clinical stu…
Vol. DistribusiPotassium is presen…
KlirensPotassium is freely…
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Silodrate Approved DB14116
small molecule | CAS: 12408-47-8

Deskripsi belum tersedia.

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small molecule

Sodium copper chlorophyllin (SCC) is a water-soluble and bright green mixture derived from natural chlorophyll that has potential antimutagenic and antioxidant properties[A227718]. This compound is used as a food colorant and supplement[A227718]. SCC of t…

Kategori:
Anti-Infective Agents, LocalAntimutagenic AgentsChlorophyll +4
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Spaglumic acid DB08835
small molecule | CAS: 4910-46-7

Spaglumic acid is the ?-aspartyl isoform of N-Acetyl-l-aspartylglutamate (isospaglumic Acid is N-(N-Acetyl-l-?-aspartyl)-l-glutamic acid). In eye drops, spaglumic acid is either a magnesium or sodium salt of N-Acetyl-l-aspartylglutamate. Spaglumic acid is a m…

Kategori:
Antiallergic Agents, Excl. CorticosteroidsDecongestants and AntiallergicsMast Cell Stabilizers +3
Target Protein:
Glutamate carboxypeptidase 2
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Sparteine DB06727
small molecule | CAS: 90-39-1

Sparteine is a plant alkaloid derived from _Cytisus scoparius_ and _Lupinus mutabilis_ which may chelate calcium and magnesium. It is a sodium channel blocker, so it falls in the category of class 1a antiarrhythmic agents. Sparteine is not currently FDA-appro…

Kategori:
AlkaloidsAntiarrhythmic agentsAntiarrhythmics, Class I +13
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Talc Approved DB09511
small molecule | CAS: 14807-96-6

Talc is a mineral composed primarily of magnesium, silicon and oxygen. It is a substance often found in cosmetic and personal hygiene products including baby powder, adult body powders and facial powders. Talc helps absorb moisture, freshen materials, and red…

Kategori:
AntiperspirantsCompounds used in a research, industrial, or household settingCosmetics +6
Waktu ParuhIntended for local …
Vol. DistribusiIntended for local …
KlirensIntended for local …
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TP-252 DB17912
small molecule | CAS: 1841444-50-5

TP-252 consists of magnesium L-lysinate bis-eicosapentaenoate, an ionizable salt of eicosapentaenoic acid (EPA), currently being investigated to treat familial adenomatous polyposis.[A259956]

Kategori:
Dietary FatsDietary Fats, UnsaturatedEicosanoids +7
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Treamid DB16365
small molecule

Treamid, also known as bisamide derivative of dicarboxylic acid (BDDA), is a complexing agent that has been found to chelate metal ions, including calcium, copper, iron, magnesium, and zinc.[A225701] This drug has shown regenerative properties and restoration…

Kategori:
Acids, AcyclicDicarboxylic Acids
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Vitamin D Approved DB11094
small molecule | CAS: 1406-16-2

Vitamin D ultimately comprises a group of lipid-soluble secosteroids responsible for a variety of biological effects, some of which include increasing the intestinal absorption of calcium, magnesium, and phosphate. With reference to human use, there are 2 mai…

Kategori:
Bone Density Conservation AgentsCytochrome P-450 CYP3A SubstratesCytochrome P-450 CYP3A4 Substrates +12
Target Protein:
Vitamin D3 receptorVitamin D-binding protein
Waktu ParuhAlthough certain st…
Vol. Distribusi-
KlirensSome studies propos…
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