Hasil Pencarian (2)
small molecule | CAS: 2326521-71-3
Adagrasib (MRTX849) is an oral, small-molecule KRAS inhibitor developed by Mirati Therapeutics. KRAS mutations are highly common in cancer and account for approximately 85% of all RAS family mutations.[A254941] However, the development of KRAS inhibitors has …
Kategori:
Antineoplastic AgentsAntineoplastic Agents, ImmunologicalAntineoplastic and Immunomodulating Agents
+21
Target Protein:
GTPase KRas
Waktu ParuhAdagrasib has a ter…
Vol. DistribusiAdagrasib has an ap…
KlirensAdagrasib has an ap…
Genetik
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small molecule | CAS: 2252403-56-6
Sotorasib, also known as AMG-510, is an acrylamide-derived KRAS inhibitor developed by Amgen.[A187547,A187556] It is indicated in the treatment of adult patients with KRAS G12C mutant non-small cell lung cancer.[L34288] This mutation makes up >50% of all KRAS…
Kategori:
Antineoplastic AgentsAntineoplastic Agents, ImmunologicalAntineoplastic and Immunomodulating Agents
+13
Target Protein:
GTPase KRas
Waktu ParuhSotorasib has a ter…
Vol. DistribusiThe volume of distr…
KlirensSotorasib has an ap…
Genetik
-